Abstract One-carbon metabolism (1CM), comprising folate metabolism and methionine
metabolism, serves as an important mechanism for cellular energy provision and the …

Cellular metabolism is crucial for various physiological processes, with folate-dependent
one-carbon (1C) metabolism playing a pivotal role. Folate, a B vitamin, is a key cofactor in …

NADH/NAD+ redox balance is pivotal for cellular metabolism. Systematic identification of
NAD (H) redox regulators, although currently lacking, would help uncover unknown effectors …

Endometrial cancer (EC) is one of the most common malignant tumors in women, and the
increasing incidence and mortality pose a serious threat to the public health. Early diagnosis …

Abstract Background One‐carbon (1C) metabolism is a metabolic network that plays
essential roles in biological reactions. In 1C metabolism, a series of nutrients are used to …

20-Hydroxyecdysone (20E) is an arthropod steroid hormone that possesses a number of
beneficial pharmacological activities in humans, including anabolic, antioxidant …

Globally, cognitive impairment (CI) is the leading cause of disability and dependency among
the elderly, presenting a significant public health concern. However, there is currently a …

Folates are B-group vitamins that function in one-carbon metabolism. Here we show that a
specific folate can activate serotonergic neurons in C. elegans to modulate behavior through …

Background SLE is a complex autoimmune disease with deleterious effects on various
organs. Accumulating evidence has shown abnormal vitamin B12 and one-carbon flux …

The crosstalk between metabolism and epigenetics is an emerging field that is gaining
importance in different areas such as cancer and aging, where changes in metabolism …