Resting-state fMRI confounds and cleanup

K Murphy, RM Birn, PA Bandettini - Neuroimage, 2013 - Elsevier
The goal of resting-state functional magnetic resonance imaging (fMRI) is to investigate the
brain's functional connections by using the temporal similarity between blood oxygenation …

Cerebrovascular reactivity (CVR) MRI with CO2 challenge: a technical review

P Liu, B Jill, H Lu - Neuroimage, 2019 - Elsevier
Cerebrovascular reactivity (CVR) is an indicator of cerebrovascular reserve and provides
important information about vascular health in a range of brain conditions and diseases …

Separating respiratory-variation-related fluctuations from neuronal-activity-related fluctuations in fMRI

RM Birn, JB Diamond, MA Smith, PA Bandettini - Neuroimage, 2006 - Elsevier
Subtle changes in a subject's breathing rate or depth, which occur naturally during rest at
low frequencies (< 0.1 Hz), have been shown to be significantly correlated with fMRI signal …

Resting fluctuations in arterial carbon dioxide induce significant low frequency variations in BOLD signal

RG Wise, K Ide, MJ Poulin, I Tracey - Neuroimage, 2004 - Elsevier
Carbon dioxide is a potent cerebral vasodilator. We have identified a significant source of
low-frequency variation in blood oxygen level-dependent (BOLD) magnetic resonance …

Detection of synchronous brain activity in white matter tracts at rest and under functional loading

Z Ding, Y Huang, SK Bailey, Y Gao… - Proceedings of the …, 2018 - National Acad Sciences
Functional MRI based on blood oxygenation level-dependent (BOLD) contrast is well
established as a neuroimaging technique for detecting neural activity in the cortex of the …

Age‐related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review

B Zimmerman, B Rypma, G Gratton… - …, 2021 - Wiley Online Library
The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …

Does functional MRI detect activation in white matter? A review of emerging evidence, issues, and future directions

JR Gawryluk, EL Mazerolle, RCN D'Arcy - Frontiers in neuroscience, 2014 - frontiersin.org
Functional magnetic resonance imaging (fMRI) is a non-invasive technique that allows for
visualization of activated brain regions. Until recently, fMRI studies have focused on gray …

The influence of carbon dioxide on brain activity and metabolism in conscious humans

F Xu, J Uh, MR Brier, J Hart Jr… - Journal of Cerebral …, 2011 - journals.sagepub.com
A better understanding of carbon dioxide (CO2) effect on brain activity may have a profound
impact on clinical studies using CO2 manipulation to assess cerebrovascular reserve and …

A method for removal of global effects from fMRI time series

PM Macey, KE Macey, R Kumar, RM Harper - Neuroimage, 2004 - Elsevier
We present a technique for removing global effects from functional magnetic resonance
imaging (fMRI) images, using a voxel-level linear model of the global signal (LMGS). The …

Relationship between respiration, end-tidal CO2, and BOLD signals in resting-state fMRI

C Chang, GH Glover - Neuroimage, 2009 - Elsevier
A significant component of BOLD fMRI physiological noise is caused by variations in the
depth and rate of respiration. It has previously been demonstrated that a breath-to-breath …