Understanding and managing in-stent restenosis: a review of clinical data, from pathogenesis to treatment

D Buccheri, D Piraino, G Andolina… - Journal of thoracic …, 2016 - pmc.ncbi.nlm.nih.gov
The lumen diameter reduction after percutaneous coronary intervention (PCI) is well known
as “restenosis”. This phenomenon is due to vessel remodeling/recoil in case of no-stent …

Restenosis, stent thrombosis, and bleeding complications: navigating between Scylla and Charybdis

J Torrado, L Buckley, A Durán, P Trujillo, S Toldo… - Journal of the American …, 2018 - jacc.org
The field of interventional cardiology has significantly evolved over 40 years by overcoming
several challenges. The introduction of first-generation drug-eluting stents significantly …

Drug-eluting stent thrombosis: current and future perspectives

S Kuramitsu, S Sonoda, K Ando, H Otake… - Cardiovascular …, 2021 - Springer
Over the past 40 years, the safety and efficacy of percutaneous coronary intervention has
dramatically improved by overcoming several challenges. The introduction of drug-eluting …

Exosome-Loaded Pro-efferocytic Vascular Stent with Lp-PLA2-Triggered Release for Preventing In-Stent Restenosis

D Zou, P Yang, J Liu, F Dai, Y **ao, A Zhao, N Huang - ACS nano, 2022 - ACS Publications
The efferocytosis defect is regarded as a pivotal event of atherosclerosis. The failure to clear
apoptotic cells in atherosclerotic plaques under vascular stents causes a failure to resolve …

Preventing treatment failures in coronary artery disease: what can we learn from the biology of in-stent restenosis, vein graft failure, and internal thoracic arteries?

C Spadaccio, C Antoniades, A Nenna… - Cardiovascular …, 2020 - academic.oup.com
Coronary artery disease (CAD) remains one of the most important causes of morbidity and
mortality worldwide, and the availability of percutaneous or surgical revascularization …

Predictors and outcomes of neoatherosclerosis in patients with in-stent restenosis: Impact of neoatherosclerosis in ISR on clinical outcome

D Nakamura, T Dohi, T Ishihara, A Kikuchi… - …, 2021 - pmc.ncbi.nlm.nih.gov
Background In-stent restenosis (ISR), especially for neoatherosclerosis, is still a major
problem of percutaneous coronary intervention (PCI) even in the drug-eluting stent (DES) …

Neoatherosclerosis after drug-eluting stent implantation: a novel clinical and therapeutic challenge

JA Borovac, D D'Amario, R Vergallo… - European Heart …, 2019 - academic.oup.com
The recognition that obstructive disease of the epicardial coronary arteries, causing
ischaemic heart disease, can be treated with a percutaneous coronary intervention (PCI) …

Prevalence and impact of neoatherosclerosis on clinical outcomes after percutaneous treatment of second-generation drug-eluting stent restenosis

Z Chen, M Matsumura, GS Mintz… - Circulation …, 2022 - ahajournals.org
Background: Clinical and morphological factors associated with lipidic versus calcified
neoatherosclerosis within second-generation drug-eluting stents and the impact of lipidic …

[HTML][HTML] Characteristics of early versus late in-stent restenosis in second-generation drug-eluting stents: an optical coherence tomography study

L Song, GS Mintz, D Yin… - …, 2017 - eurointervention.pcronline.com
Aims: In-stent restenosis (ISR) is an important cause of drug-eluting stent (DES) failure and
target vessel revascularisation. In this study we aimed to evaluate differences between early …

Temporal course of vascular healing and neoatherosclerosis after implantation of durable-or biodegradable-polymer drug-eluting stents

G Guagliumi, K Shimamura, V Sirbu… - European heart …, 2018 - academic.oup.com
Aims Delayed healing and endothelial dysfunction may occur with drug-eluting stents (DES),
promoting accelerated infiltration of lipids in the neointima and development of …