Polymers without petrochemicals: sustainable routes to conventional monomers

G Hayes, M Laurel, D MacKinnon, T Zhao… - Chemical …, 2022 - ACS Publications
Access to a wide range of plastic materials has been rationalized by the increased demand
from growing populations and the development of high-throughput production systems …

Metabolic engineering: methodologies and applications

MJ Volk, VG Tran, SI Tan, S Mishra, Z Fatma… - Chemical …, 2022 - ACS Publications
Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance

HN Bell, RJ Rebernick, J Goyert, R Singhal, M Kuljanin… - Cancer cell, 2022 - cell.com
Microbial dysbiosis is a colorectal cancer (CRC) hallmark and contributes to inflammation,
tumor growth, and therapy response. Gut microbes signal via metabolites, but how the …

Sustainable production and degradation of plastics using microbes

SY Choi, Y Lee, HE Yu, IJ Cho, M Kang, SY Lee - Nature Microbiology, 2023 - nature.com
Plastics are indispensable in everyday life and industry, but the environmental impact of
plastic waste on ecosystems and human health is a huge concern. Microbial biotechnology …

A comprehensive metabolic map for production of bio-based chemicals

SY Lee, HU Kim, TU Chae, JS Cho, JW Kim, JH Shin… - Nature …, 2019 - nature.com
Production of industrial chemicals using renewable biomass feedstock is becoming
increasingly important to address limited fossil resources, climate change and other …

Escherichia coli as a host for metabolic engineering

S Pontrelli, TY Chiu, EI Lan, FYH Chen, P Chang… - Metabolic …, 2018 - Elsevier
Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …

[HTML][HTML] A field of dreams: Lignin valorization into chemicals, materials, fuels, and health-care products

J Becker, C Wittmann - Biotechnology Advances, 2019 - Elsevier
Lignin is one of the most abundant renewable resources on earth and is readily produced as
a sidestream during biomass fractioning. So far, these large quantities of lignin have been …

Microbial metabolite signaling is required for systemic iron homeostasis

NK Das, AJ Schwartz, G Barthel, N Inohara, Q Liu… - Cell metabolism, 2020 - cell.com
Iron is a central micronutrient needed by all living organisms. Competition for iron in the
intestinal tract is essential for the maintenance of indigenous microbial populations and for …

Formation and functionalization of membraneless compartments in Escherichia coli

SP Wei, ZG Qian, CF Hu, F Pan, MT Chen… - Nature chemical …, 2020 - nature.com
Membraneless organelles formed by liquid–liquid phase separation of proteins or nucleic
acids are involved in diverse biological processes in eukaryotes. However, such cellular …

Recent advances in systems metabolic engineering tools and strategies

TU Chae, SY Choi, JW Kim, YS Ko, SY Lee - Current opinion in …, 2017 - Elsevier
Highlights•Microbial cell factories are becoming important in sustainable chemical
production.•Systems metabolic engineering allows efficient microbial cell factory …