Edema and brain trauma

AW Unterberg, J Stover, B Kress, KL Kiening - Neuroscience, 2004 - Elsevier
Brain edema leading to an expansion of brain volume has a crucial impact on morbidity and
mortality following traumatic brain injury (TBI) as it increases intracranial pressure, impairs …

[HTML][HTML] The water transport system in astrocytes–aquaporins

Z Zhou, J Zhan, Q Cai, F Xu, R Chai, K Lam, Z Luan… - Cells, 2022 - mdpi.com
Highlights (AQPs) are transmembrane proteins responsible for fast water movement across
cell membranes, including those of astrocytes. The expression and subcellular localization …

Fluid dynamics inside the brain barrier: current concept of interstitial flow, glymphatic flow, and cerebrospinal fluid circulation in the brain

T Nakada, IL Kwee - The Neuroscientist, 2019 - journals.sagepub.com
The discovery of the water specific channel, aquaporin, and abundant expression of its
isoform, aquaporin-4 (AQP-4), on astrocyte endfeet brought about significant advancements …

[HTML][HTML] Pathophysiology, management, and therapeutics in subarachnoid hemorrhage and delayed cerebral ischemia: an overview

HW Sanicola, CE Stewart, P Luther, K Yabut… - Pathophysiology, 2023 - mdpi.com
Subarachnoid hemorrhage (SAH) is a type of hemorrhagic stroke resulting from the rupture
of an arterial vessel within the brain. Unlike other stroke types, SAH affects both young …

Aquaporin and brain diseases

J Badaut, AM Fukuda, A Jullienne, KG Petry - Biochimica et Biophysica …, 2014 - Elsevier
Background The presence of water channel proteins, aquaporins (AQPs), in the brain led to
intense research in understanding the underlying roles of each of them under normal …

Cerebral vasospasm after subarachnoid hemorrhage: the emerging revolution

RL Macdonald, RM Pluta, JH Zhang - Nature clinical practice Neurology, 2007 - nature.com
Cerebral vasospasm is the classic cause of delayed neurological deterioration after
aneurysmal subarachnoid hemorrhage, leading to cerebral ischemia and infarction, and …

Molecular mechanisms of brain tumor edema

MC Papadopoulos, S Saadoun, DK Binder, GT Manley… - Neuroscience, 2004 - Elsevier
Despite their diverse histological types, most brain tumours cause brain oedema, which is a
significant cause of patient morbidity and mortality. Brain tumour oedema occurs when …

A clinical primer for the glymphatic system

LP Carlstrom, A Eltanahy, A Perry, AA Rabinstein… - Brain, 2022 - academic.oup.com
The complex and dynamic system of fluid flow through the perivascular and interstitial
spaces of the CNS has new-found implications for neurological diseases. CSF movement …

Molecular mechanisms of early brain injury after subarachnoid hemorrhage

RP Ostrowski, AR Colohan, JH Zhang - Neurological research, 2006 - Taylor & Francis
Objectives: Increasing body of experimental and clinical data indicates that early brain injury
after initial bleeding largely contributes to unfavorable outcome after subarachnoid …

[HTML][HTML] Expression of acute-phase response proteins in retinal Muller cells in diabetes

C Gerhardinger, MB Costa, MC Coulombe… - … & visual science, 2005 - arvojournals.org
purpose. To characterize the whole spectrum of gene expression changes induced by
diabetes in retinal Müller glial cells. methods. Müller cells were isolated from the retina of …