Luteolin, a potent anticancer compound: from chemistry to cellular interactions and synergetic perspectives

H Singh Tuli, P Rath, A Chauhan, K Sak, D Aggarwal… - Cancers, 2022 - mdpi.com
Simple Summary Common flavonoid luteolin 3′, 4′, 5, 7-tetrahydroxyflavone has
immense potential to be utilized as a chemopreventive dietary molecule. According to …

Polyphenol-loaded nano-carriers for breast cancer therapy: a comprehensive review

AA Bhat, G Gupta, M Afzal, R Thapa, H Ali… - BioNanoScience, 2024 - Springer
Breast cancer remains a significant global health challenge, demanding innovative
therapeutic approaches. Polyphenols, a class of natural compounds widely distributed in …

Luteolin inhibits triple-negative breast cancer by inducing apoptosis and autophagy through SGK1-FOXO3a-BNIP3 signaling

L Wu, Y Lin, S Gao, Y Wang, H Pan, Z Wang… - Frontiers in …, 2023 - frontiersin.org
Background: Triple-negative breast cancer (TNBC) is one of the most prominent neoplasm
disorders and lacks efficacious treatments yet. Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone) …

Vaccines in breast cancer: challenges and breakthroughs

GN Fatima, H Fatma, SK Saraf - Diagnostics, 2023 - mdpi.com
Breast cancer is a problem for women's health globally. Early detection techniques come in
a variety of forms ranging from local to systemic and from non-invasive to invasive. The …

Application of luteolin in neoplasms and nonneoplastic diseases

K Rakoczy, J Kaczor, A Sołtyk, N Szymańska… - International Journal of …, 2023 - mdpi.com
Researchers are amazed at the multitude of biological effects of 3′, 4′, 5, 7-
tetrahydroxyflavone, more commonly known as luteolin, as it simultaneously has antioxidant …

Revisiting luteolin: An updated review on its anticancer potential

A Rauf, P Wilairatana, PB Joshi, Z Ahmad, A Olatunde… - Heliyon, 2024 - cell.com
Numerous natural products found in our diet, such as polyphenols and flavonoids, can
prevent the progression of cancer. Luteolin, a natural flavone, present in significant amounts …

The Southern European atlantic diet and its supplements: The chemical bases of its anticancer properties

PG Vivanco, P Taboada, A Coelho - Nutrients, 2023 - mdpi.com
Scientific evidence increasingly supports the strong link between diet and health,
acknowledging that a well-balanced diet plays a crucial role in preventing chronic diseases …

Fighting carcinogenesis with plant metabolites by weakening proliferative signaling and disabling replicative immortality networks of rapidly dividing and invading …

AK Wani, N Akhtar, A Sharma… - Current Drug …, 2023 - ingentaconnect.com
Background: Cancer, an uncontrolled multistage disease causing swift division of cells, is a
leading disease with the highest mortality rate. Cellular heterogeneity, evading growth …

Molecular Mechanisms of Flavonoids against Tumor Gamma-Herpesviruses and Their Correlated Cancers—A Focus on EBV and KSHV Life Cycles and …

STS Hassan, M Šudomová - International Journal of Molecular Sciences, 2022 - mdpi.com
Epstein–Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV) are cancer-
causing viruses that belong to human gamma-herpesviruses. They are DNA viruses known …

[HTML][HTML] Opportunities, obstacles and current challenges of flavonoids for luminal and triple-negative breast cancer therapy

VS Vachetta, M Marder, MF Troncoso… - European Journal of …, 2022 - Elsevier
Flavonoids are a large group of polyphenols with numerous biological effects on cancer
cells. They have been shown to affect proliferation via cell cycle arrest, apoptosis and …