Pathology of triple negative breast cancer
F Borri, A Granaglia - Seminars in cancer biology, 2021 - Elsevier
Triple negative breast cancer (TNBC) is a subtype of breast tumor lacking hormone
receptors expression and HER2 gene amplification and represents 24% of newly diagnosed …
receptors expression and HER2 gene amplification and represents 24% of newly diagnosed …
Tracking cancer evolution through the disease course
During cancer evolution, constituent tumor cells compete under dynamic selection
pressures. Phenotypic variation can be observed as intratumor heterogeneity, which is …
pressures. Phenotypic variation can be observed as intratumor heterogeneity, which is …
Simvastatin induced ferroptosis for triple-negative breast cancer therapy
X Yao, R ** the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking
Circulating tumour DNA (ctDNA) allows tracking of the evolution of human cancers at high
resolution, overcoming many limitations of tissue biopsies. However, exploiting ctDNA to …
resolution, overcoming many limitations of tissue biopsies. However, exploiting ctDNA to …
Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy
Genomic changes observed across treatment may result from either clonal evolution or
geographically disparate sampling of heterogeneous tumors. Here we use computational …
geographically disparate sampling of heterogeneous tumors. Here we use computational …
Effect of neoadjuvant therapy on breast cancer biomarker profile
L Rey-Vargas, JC Mejía-Henao, MC Sanabria-Salas… - BMC cancer, 2020 - Springer
Background Breast cancer clinical management requires the assessment of hormone
receptors (estrogen (ER) and progesterone receptor (PR)), human epidermal growth factor …
receptors (estrogen (ER) and progesterone receptor (PR)), human epidermal growth factor …
Unraveling the molecular mechanisms of lymph node metastasis in ovarian cancer: focus on MEOX1
J Li, Y Sun, X Zhi, Y Sun, Z Abudousalamu… - Journal of Ovarian …, 2024 - Springer
Background Lymph node metastasis (LNM) is a major factor contributing to the high mortality
rate of ovarian cancer, making the treatment of this disease challenging. However, the …
rate of ovarian cancer, making the treatment of this disease challenging. However, the …