Severe fever with thrombocytopenia syndrome virus: a highly lethal bunyavirus

J Li, S Li, L Yang, P Cao, J Lu - Critical Reviews in Microbiology, 2021 - Taylor & Francis
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel bunyavirus. Since
2007, SFTS disease has been reported in China with high fatality rate up to 30%, which …

[HTML][HTML] Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC

KL Siu, KS Yuen, C Castaño-Rodriguez, ZW Ye… - The FASEB …, 2019 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus (SARS-CoV) is capable of inducing a storm
of proinflammatory cytokines. In this study, we show that the SARS-CoV open reading frame …

Viral evasion strategies in type I IFN signaling–a summary of recent developments

KS Schulz, KL Mossman - Frontiers in immunology, 2016 - frontiersin.org
The immune system protects the organism against infections and the damage associated
with them. The first line of defense against pathogens is the innate immune response. In the …

Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3

PY Lui, LYR Wong, CL Fung, KL Siu… - Emerging microbes & …, 2016 - Taylor & Francis
Middle East respiratory syndrome coronavirus (MERS-CoV) infection has claimed hundreds
of lives and has become a global threat since its emergence in Saudi Arabia in 2012. The …

Selective activation of type II interferon signaling by Zika virus NS5 protein

V Chaudhary, KS Yuen, JFW Chan, CP Chan… - Journal of …, 2017 - Am Soc Microbiol
Severe complications of Zika virus (ZIKV) infection might be caused by inflammation, but
how ZIKV induces proinflammatory cytokines is not understood. In this study, we show …

A Look into Bunyavirales Genomes: Functions of Non-Structural (NS) Proteins

SS Leventhal, D Wilson, H Feldmann, DW Hawman - Viruses, 2021 - mdpi.com
In 2016, the Bunyavirales order was established by the International Committee on
Taxonomy of Viruses (ICTV) to incorporate the increasing number of related viruses across …

Viral evasion of the interferon response at a glance

J Zhu, C Chiang, MU Gack - Journal of Cell Science, 2023 - journals.biologists.com
Re-emerging and new viral pathogens have caused significant morbidity and mortality
around the world, as evidenced by the recent monkeypox, Ebola and Zika virus outbreaks …

Single-cell landscape of peripheral immune responses to fatal SFTS

H Li, X Li, S Lv, X Peng, N Cui, T Yang, Z Yang, C Yuan… - Cell reports, 2021 - cell.com
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease
with high fatality. Poor prognosis of SFTS has been associated with dysregulated host …

Physiological functions of RIG-I-like receptors

M Yoneyama, H Kato, T Fujita - Immunity, 2024 - cell.com
RIG-I-like receptors (RLRs) are crucial for pathogen detection and triggering immune
responses and have immense physiological importance. In this review, we first summarize …

Baseline map** of severe fever with thrombocytopenia syndrome virology, epidemiology and vaccine research and development

NE Bopp, JA Kaiser, AE Strother, ADT Barrett… - NPJ vaccines, 2020 - nature.com
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a newly emergent tick-borne
bunyavirus first discovered in 2009 in China. SFTSV is a growing public health problem that …