Ultrasound nanotheranostics: Toward precision medicine

Y Qin, X Geng, Y Sun, Y Zhao, W Chai, X Wang… - Journal of Controlled …, 2023 - Elsevier
Ultrasound (US) is a mechanical wave that can penetrate biological tissues and trigger
complex bioeffects. The mechanisms of US in different diagnosis and treatment are different …

[HTML][HTML] Tumor spheroids as model to design acoustically mediated drug therapies: A review

M Roy, C Alix, A Bouakaz, S Serrière, JM Escoffre - Pharmaceutics, 2023 - mdpi.com
Tumor spheroids as well as multicellular tumor spheroids (MCTSs) are promising 3D in vitro
tumor models for drug screening, drug design, drug targeting, drug toxicity, and validation of …

A spatiotemporal computational model of focused ultrasound heat-induced nano-sized drug delivery system in solid tumors

F Moradi Kashkooli, M Souri, J Tavakkoli… - Drug delivery, 2023 - Taylor & Francis
Focused Ultrasound (FUS)-triggered nano-sized drug delivery, as a smart stimuli-responsive
system for treating solid tumors, is computationally investigated to enhance localized …

Turning down the heat: The case for mild hyperthermia and thermosensitive liposomes

M Regenold, P Bannigan, JC Evans, A Waspe… - … , Biology and Medicine, 2022 - Elsevier
Abstract “A single disappointing study does not mean an end to the future of ThermoDox®”,
writes Michael Tardugno (CEO of Celsion Corporation), after announcing the termination of …

Reversible cross-linked thermoresponsive polycaprolactone micelles for enhanced stability and controlled release

A Bhadran, H Polara, EL Calubaquib, H Wang… - …, 2023 - ACS Publications
Thermoresponsive amphiphilic poly (ε-caprolactone) s (PCL) s are excellent candidates for
drug delivery due to their biodegradability, biocompatibility, and controlled release …

Pharmacokinetic behaviors of soft nanoparticulate formulations of chemotherapeutics

M Sarkar, Y Wang, O Ekpenyong… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Chemotherapeutic treatment with conventional drug formulations pose numerous
challenges, such as poor solubility, high cytotoxicity and serious off‐target side effects, low …

RETRACTED ARTICLE: Investigation of Eutectic Mixtures of Fatty Acids as a Novel Construct for Temperature-Responsive Drug Delivery

F Parveen, A Madni, VP Torchilin… - International journal …, 2022 - Taylor & Francis
Parveen F, Madni A, Torchilin VP, et al. Int J Nanomedicine. 2022; 17: 2413–2434. We, the
Editors and Publisher of International Journal of Nanomedicine, have retracted the following …

Ultrawide bandwidth high-frequency ultrasonic transducers with gradient acoustic impedance matching layer for biomedical imaging

J Zhao, Z Li, C Fei, C Hou, D Wang… - IEEE Transactions …, 2022 - ieeexplore.ieee.org
The high-frequency ultrasonic transducers with larger bandwidths yield excellent imaging
performance in the biomedical field. However, achieving perfect acoustic impedance …

[HTML][HTML] Delivering Volumetric Hyperthermia to Head and Neck Cancer Patient-Specific Models Using an Ultrasound Spherical Random Phased Array Transducer

M Zubair, I Uddin, R Dickinson, CJ Diederich - Bioengineering, 2024 - mdpi.com
In exploring adjuvant therapies for head and neck cancer, hyperthermia (40–45° C) has
shown efficacy in enhancing chemotherapy and radiation, as well as the delivery of …

Mathematical modelling of nanoparticle-mediated topical drug delivery to skin tissue

K McLean, W Zhan - International Journal of Pharmaceutics, 2022 - Elsevier
Nanoparticles have been extensively studied to improve drug delivery outcomes, however,
their use in topical delivery remains controversial. Although the feasibility to cross the human …