More than a biomarker: could language be a biosocial marker of psychosis?

L Palaniyappan - npj Schizophrenia, 2021 - nature.com
Automated extraction of quantitative linguistic features has the potential to predict objectively
the onset and progression of psychosis. These linguistic variables are often considered to …

Dissecting the neurobiology of linguistic disorganisation and impoverishment in schizophrenia

L Palaniyappan - Seminars in cell & developmental biology, 2022 - Elsevier
Schizophrenia provides a quintessential disease model of how disturbances in the
molecular mechanisms of neurodevelopment lead to disruptions in the emergence of …

Natural language processing methods are sensitive to sub-clinical linguistic differences in schizophrenia spectrum disorders

SX Tang, R Kriz, S Cho, SJ Park, J Harowitz, RE Gur… - npj …, 2021 - nature.com
Computerized natural language processing (NLP) allows for objective and sensitive
detection of speech disturbance, a hallmark of schizophrenia spectrum disorders (SSD). We …

[HTML][HTML] Quantified language connectedness in schizophrenia-spectrum disorders

AE Voppel, JN de Boer, SG Brederoo, HG Schnack… - Psychiatry …, 2021 - Elsevier
Abstract Language abnormalities are a core symptom of schizophrenia-spectrum disorders
and could serve as a potential diagnostic marker. Natural language processing enables …

Acoustic speech markers for schizophrenia-spectrum disorders: a diagnostic and symptom-recognition tool

JN De Boer, AE Voppel, SG Brederoo… - Psychological …, 2023 - cambridge.org
Background Clinicians routinely use impressions of speech as an element of mental status
examination. In schizophrenia-spectrum disorders, descriptions of speech are used to …

Progressive changes in descriptive discourse in First Episode Schizophrenia: a longitudinal computational semantics study

MF Alonso-Sánchez, SD Ford, M MacKinley, A Silva… - Schizophrenia, 2022 - nature.com
Computational semantics, a branch of computational linguistics, involves automated
meaning analysis that relies on how words occur together in natural language. This offers a …

Construct validity for computational linguistic metrics in individuals at clinical risk for psychosis: associations with clinical ratings

ZR Bilgrami, C Sarac, A Srivastava, SN Herrera… - Schizophrenia …, 2022 - Elsevier
Abstract Language deficits are prevalent in psychotic illness, including its risk states, and are
related to marked impairment in functioning. It is therefore important to characterize …

Syntactic complexity of spoken language in the diagnosis of schizophrenia: A probabilistic Bayes network model

AM Silva, R Limongi, M MacKinley, SD Ford… - Schizophrenia …, 2023 - Elsevier
In the clinical linguistics of schizophrenia, syntactic complexity has received much attention.
In this study, we address whether syntactic complexity deteriorates within the six months …

Automatic language analysis identifies and predicts schizophrenia in first-episode of psychosis

A Figueroa-Barra, D Del Aguila, M Cerda, PA Gaspar… - Schizophrenia, 2022 - nature.com
Automated language analysis of speech has been shown to distinguish healthy control (HC)
vs chronic schizophrenia (SZ) groups, yet the predictive power on first-episode psychosis …

Syntactic complexity and diversity of spontaneous speech production in schizophrenia spectrum and major depressive disorders

K Schneider, K Leinweber, H Jamalabadi… - Schizophrenia, 2023 - nature.com
Abstract Syntax, the grammatical structure of sentences, is a fundamental aspect of
language. It remains debated whether reduced syntactic complexity is unique to …