Mesenchymal Stem Cells‐Derived Small Extracellular Vesicles and Their Validation as a Promising Treatment for Chondrosarcoma in a 3D Model in Vitro

E Romano, F Perut, S Avnet… - Biotechnology and …, 2024 - Wiley Online Library
ABSTRACT Chondrosarcomas (CHS) constitute approximately 20% of all primary malignant
bone tumors, characterized by a slow growth rate with initial manifestation of few signs and …

Mammalian perfusion cultivation at high L-Arginine concentration for efficient production of recombinant protein by increasing perfusion filter transmission

BR Poulsen, T Egebjerg, M Noebel, K Thorsen… - Journal of …, 2024 - Elsevier
Abstract Cultivations of Chinese Hamster Ovary (CHO) cells in a perfusion setup were
conducted in the presence of super physiological concentrations of L-Arginine to investigate …