Retrotransposon-mediated disruption of a chitin synthase gene confers insect resistance to Bacillus thuringiensis Vip3Aa toxin

Z Liu, C Liao, L Zou, M **, Y Shan, Y Quan, H Yao… - PLoS …, 2024 - journals.plos.org
The vegetative insecticidal protein Vip3Aa from Bacillus thuringiensis (Bt) has been
produced by transgenic crops to counter pest resistance to the widely used crystalline (Cry) …

Downregulation of a transcription factor associated with resistance to Bt toxin Vip3Aa in the invasive fall armyworm

M **, Y Shan, Y Peng, W Wang… - Proceedings of the …, 2023 - National Acad Sciences
Transgenic crops producing insecticidal proteins from Bacillus thuringiensis (Bt) have
revolutionized control of some major pests. However, more than 25 cases of field-evolved …

Structural changes upon membrane insertion of the insecticidal pore-forming toxins produced by Bacillus thuringiensis

S Pacheco, I Gómez, AE Peláez-Aguilar… - Frontiers in Insect …, 2023 - frontiersin.org
Different Bacillus thuringiensis (Bt) strains produce a broad variety of pore-forming toxins
(PFTs) that show toxicity against insects and other invertebrates. Some of these insecticidal …

Expression of mosquito miRNAs in entomopathogenic fungus induces pathogen-mediated host RNA interference and increases fungal efficacy

C Cui, Y Wang, Y Li, P Sun, J Jiang, H Zhou, J Liu… - Cell Reports, 2022 - cell.com
The growing threat of insecticide resistance prompts the urgent need to develop additional
tools for mosquito control. Entomopathogenic fungi provide an eco-friendly alternative to …

Reduced toxin binding associated with resistance to Vip3Aa in the corn earworm (Helicoverpa zea)

DD Kerns, F Yang, DL Kerns, SD Stewart… - Applied and …, 2023 - Am Soc Microbiol
Transgenic corn and cotton that express Cry and Vip insecticidal proteins from the
bacterium, Bacillus thuringiensis (Bt), have been valuable tools for the management of …

PHB2 affects the virulence of Vip3Aa to Sf9 cells through internalization and mitochondrial stability

B An, Y Zhang, X Li, X Hou, B Yan, J Cai - Virulence, 2022 - Taylor & Francis
The vegetative insecticidal proteins (Vip3A) secreted by some Bacillus thuringiensis (Bt)
strains during vegetative growth are regarded as a new generation of insecticidal toxins …

Critical Domains in the Specific Binding of Radiolabeled Vip3Af Insecticidal Protein to Brush Border Membrane Vesicles from Spodoptera spp. and Cultured Insect …

Y Quan, M Lázaro-Berenguer… - Applied and …, 2021 - Am Soc Microbiol
Vegetative insecticidal proteins (Vip3) from Bacillus thuringiensis have been used, in
combination with Cry proteins, to better control insect pests and as a strategy to delay the …

[HTML][HTML] A strategy to enhance the insecticidal potency of Vip3Aa by introducing additional cleavage sites to increase its proteolytic activation efficiency

K Jiang, Z Chen, Y Shi, Y Zang, C Shang… - Engineering …, 2023 - Elsevier
Microbially derived, protein-based biopesticides have become a vital element in pest
management strategies. Vip3 family proteins from Bacillus thuringiensis have distinct …

Responses to Bt toxin Vip3Aa by pink bollworm larvae resistant or susceptible to Cry toxins

BE Tabashnik, GC Unnithan, AJ Yelich… - Pest Management …, 2022 - Wiley Online Library
BACKGROUND Transgenic crops that make insecticidal proteins from Bacillus thuringiensis
(Bt) have revolutionized management of some pests. However, evolution of resistance to Bt …

Inheritance and Fitness Costs of Vip3Aa19 Resistance in Mythimna separata

Y Wang, J Yang, T Zhang, S Bai, Z Wang, K He - Toxins, 2022 - mdpi.com
The “high-dose/refuge” strategy is expected to work most effectively when resistance is
inherited as a functionally recessive trait and the fitness costs associated with resistance are …