Brain tumors, although rare, contribute to distinct mortality and morbidity at all ages.
Although there are few therapeutic options for brain tumors, enhanced biological …

Brain tumors remain one of the most difficult tumors to treat and, depending on the
diagnosis, have a poor prognosis. Of brain tumors, glioblastoma (GBM) is the most common …

Meningiomas are the most common primary intracranial tumors. There are no effective
medical therapies for meningioma patients, and new treatments have been encumbered by …

PURPOSE Meningiomas are the most frequent primary intracranial tumors. Patient outcome
varies widely from benign to highly aggressive, ultimately fatal courses. Reliable …

One-fifth of meningiomas classified as benign by World Health Organization (WHO)
histopathological grading will behave malignantly. To better diagnose these tumors, several …

Meningiomas are the most common primary central nervous system neoplasm. Despite
promising recent progress in elucidating the genomic landscape and underlying biology of …

Background Meningiomas, the most common primary intracranial tumors, can be separated
into 3 DNA methylation groups with distinct biological drivers, clinical outcomes, and …

Glioblastoma ranks among the most aggressive and lethal of all human cancers. Self-
renewing, highly tumorigenic glioblastoma stem cells (GSCs) contribute to therapeutic …

YAP1 is a transcriptional coactivator regulated by the Hippo signaling pathway, including
NF2. Meningiomas are the most common primary brain tumors; a large percentage exhibit …

Meningiomas, the most common primary brain tumors in adults, are often benign and
curable by surgical resection. However, a subset is of higher grade, shows aggressive …