The prevalence of cardiovascular disease (CVD) is increasing over time. CVD is a
comorbidity in diabetes and contributes to premature death. Citrus flavonoids possess …

Prenylated flavonoids are a special kind of flavonoid derivative possessing one or more
prenyl groups in the parent nucleus of the flavonoid. The presence of the prenyl side chain …

Plants of the genus Centaurea have been widely used as natural therapeutics in different
countries. This study investigated the antioxidant–structure activity relationship of eight …

Oxidative stress plays a major role in the development and progression of diabetic
nephropathy (DN). In this study, the potential protective effect of ginger (Zingiber officinale) …

Cyclophosphamide (CP) is a widely used chemotherapeutic agent; however, its clinical
application is limited because of its multi-organ toxicity. Galangin (Gal) is a bioactive …

Drug-induced nephrotoxicity contributes to acute kidney injury (AKI) and represents a major
problem in the clinical setting. We investigated the possible involvement of NLRP3 …

Abstract β-Glucuronidase, a crucial enzyme in drug metabolism and detoxification,
represents a promising target for therapeutic intervention due to its potential to modulate …

Berberine (BBR) is a natural isoquinoline alkaloid with very impressive health benefits. It is
one of the most effective natural supplements available; however, its ameliorative …

Umbelliferone (UMB) is a coumarin derivative with promising hepatoprotective effects. In this
study, we examined the possible protective effects of UMB against cyclophosphamide (CP) …

Olive leaf extract (OLE) has potential health benefits and protects against cytotoxicity in
different organs. However, nothing has yet been reported on its potential to prevent …