The human connectome in Alzheimer disease—relationship to biomarkers and genetics
The pathology of Alzheimer disease (AD) damages structural and functional brain networks,
resulting in cognitive impairment. The results of recent connectomics studies have now …
resulting in cognitive impairment. The results of recent connectomics studies have now …
Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease
Subjective cognitive decline (SCD) is regarded as the first clinical manifestation in the
Alzheimer's disease (AD) continuum. Investigating populations with SCD is important for …
Alzheimer's disease (AD) continuum. Investigating populations with SCD is important for …
[HTML][HTML] A review of the application of deep learning in the detection of Alzheimer's disease
S Gao, D Lima - International Journal of Cognitive Computing in …, 2022 - Elsevier
Alzheimer's disease (AD) is the most common chronic disease in the elderly, with a high
incidence rate. In recent years, deep learning has become popular in the field of medical …
incidence rate. In recent years, deep learning has become popular in the field of medical …
[HTML][HTML] Fractal dimension of the brain in neurodegenerative disease and dementia: A systematic review
Sensitive and specific antemortem biomarkers of neurodegenerative disease and dementia
are crucial to the pursuit of effective treatments, required both to reliably identify disease and …
are crucial to the pursuit of effective treatments, required both to reliably identify disease and …
Minor neuropsychological deficits in patients with subjective cognitive decline
S Wolfsgruber, L Kleineidam, J Guski, A Polcher… - Neurology, 2020 - AAN Enterprises
Objective To determine the nature and extent of minor neuropsychological deficits in
patients with subjective cognitive decline (SCD) and their association with CSF biomarkers …
patients with subjective cognitive decline (SCD) and their association with CSF biomarkers …
[HTML][HTML] Open science datasets from PREVENT-AD, a longitudinal cohort of pre-symptomatic Alzheimer's disease
Abstract To move Alzheimer Disease (AD) research forward it is essential to collect data
from large cohorts, but also make such data available to the global research community. We …
from large cohorts, but also make such data available to the global research community. We …
[HTML][HTML] Distinct disruptive patterns of default mode subnetwork connectivity across the spectrum of preclinical Alzheimer's disease
C Xue, B Yuan, Y Yue, J Xu, S Wang, M Wu… - Frontiers in Aging …, 2019 - frontiersin.org
Background: The early progression continuum of Alzheimer's disease (AD) has been
considered to advance through subjective cognitive decline (SCD), non-amnestic mild …
considered to advance through subjective cognitive decline (SCD), non-amnestic mild …
Detecting early cognitive decline in alzheimer's disease with brain synaptic structural and functional evaluation
S Ribarič - Biomedicines, 2023 - mdpi.com
Early cognitive decline in patients with Alzheimer's (AD) is associated with quantifiable
structural and functional connectivity changes in the brain. AD dysregulation of Aβ and tau …
structural and functional connectivity changes in the brain. AD dysregulation of Aβ and tau …
Lifelong experiences as a proxy of cognitive reserve moderate the association between connectivity and cognition in Alzheimer's disease
E Ersoezlue, BS Rauchmann, T Schneider-Axmann… - Neurobiology of …, 2023 - Elsevier
Alzheimer's disease (AD) is associated with alterations in functional connectivity (FC) of the
brain. The FC underpinnings of CR, that is, lifelong experiences, are largely unknown …
brain. The FC underpinnings of CR, that is, lifelong experiences, are largely unknown …
Cerebral hyperactivation across the Alzheimer's disease pathological cascade
Neuronal dysfunction in specific brain regions or across distributed brain networks is a
known feature of Alzheimer's disease. An often reported finding in the early stage of the …
known feature of Alzheimer's disease. An often reported finding in the early stage of the …