Interleukin-17A (IL-17A), a key molecule of innate and adaptive immunity, and its potential involvement in COVID-19-related thrombotic and vascular mechanisms
Discussion Taking all these various pieces of evidence (albeit minimal), we would like to
hypothesize that in COVID-19 patients, IL-17A could potentially promote a pro-thrombotic …
hypothesize that in COVID-19 patients, IL-17A could potentially promote a pro-thrombotic …
Neutrophil extracellular traps mediate deep vein thrombosis: from mechanism to therapy
M Yao, J Ma, D Wu, C Fang, Z Wang, T Guo… - Frontiers in …, 2023 - frontiersin.org
Deep venous thrombosis (DVT) is a part of venous thromboembolism (VTE) that clinically
manifests as swelling and pain in the lower limbs. The most serious clinical complication of …
manifests as swelling and pain in the lower limbs. The most serious clinical complication of …
Modeling thrombosis in silico: Frontiers, challenges, unresolved problems and milestones
Hemostasis is a complex physiological mechanism that functions to maintain vascular
integrity under any conditions. Its primary components are blood platelets and a coagulation …
integrity under any conditions. Its primary components are blood platelets and a coagulation …
A mathematical model to quantify the effects of platelet count, shear rate, and injury size on the initiation of blood coagulation under venous flow conditions
Platelets upregulate the generation of thrombin and reinforce the fibrin clot which increases
the incidence risk of venous thromboembolism (VTE). However, the role of platelets in the …
the incidence risk of venous thromboembolism (VTE). However, the role of platelets in the …
Multiphase continuum modeling of thrombosis in aneurysms and recirculation zones
Aneurysms of saccular shape are usually associated with a slow, almost stagnant blood
flow, as well as a consequent emergence of blood clots. Despite the practical importance …
flow, as well as a consequent emergence of blood clots. Despite the practical importance …
Th2 and Th17‐associated immunopathology following SARS‐CoV‐2 breakthrough infection in Spike‐vaccinated ACE2‐humanized mice
T Zhang, N Magazine, MC McGee… - Journal of Medical …, 2024 - Wiley Online Library
Vaccines have demonstrated remarkable effectiveness in protecting against COVID‐19;
however, concerns regarding vaccine‐associated enhanced respiratory diseases (VAERD) …
however, concerns regarding vaccine‐associated enhanced respiratory diseases (VAERD) …
Patient-specific modelling of blood coagulation
Blood coagulation represents one of the most studied processes in biomedical modelling.
However, clinical applications of this modelling remain limited because of the complexity of …
However, clinical applications of this modelling remain limited because of the complexity of …
Multiphase patient-specific simulations to study fibrillation-induced thrombosis in the left atrial appendage
Thrombosis commonly develops in the left atrial appendage of patients with atrial fibrillation.
The formation of blood clots in atrial appendage is a complex process, which depends on …
The formation of blood clots in atrial appendage is a complex process, which depends on …
A multiscale model of platelet-fibrin thrombus growth in the flow
Thrombosis is a life-threatening clinical condition characterized by the obstruction of blood
flow in a vessel due to the formation of a large thrombus. The pathogenesis of thrombosis is …
flow in a vessel due to the formation of a large thrombus. The pathogenesis of thrombosis is …
Quality marker prediction in Trillium tschonoskii based on UHPLC–MS chemical characterisation and network pharmacology
Z Wang, R Fu, N Zhu, J Wang, X Zhang… - Phytochemical …, 2023 - Wiley Online Library
Introduction As a folk herbal medicine, Trillium tschonoskii has been used for thousands of
years. However, due to the complexity of the chemical constituents of this herb, few …
years. However, due to the complexity of the chemical constituents of this herb, few …