Nanobodies can be seen as next‐generation tools for the recognition and modulation of
antigens that are inaccessible to conventional antibodies. Due to their compact structure and …

Over the past two decades, develo** medical applications for peptides has, and continues
to be a highly active area of research. At present there are over 60 peptide‐based drugs on …

We describe a new technique in protein synthesis that extends the existing repertoire of
methods for protein modification: A chemoselective reaction that induces reactivity for a …

Intracellular delivery of therapeutic proteins is highly challenging and in most cases requires
chemical or genetic modifications. Herein, two complementary approaches for endocytosis …

Multidrug‐resistant bacteria represent one of the biggest challenges facing modern
medicine. The increasing prevalence of glycopeptide resistance compromises the efficacy of …

Modifying cyclic cell‐penetrating deca‐arginine (cR10) peptides with 4‐(4‐
dimethylaminophenylazo) benzoic acid (DABCYL) improves the uptake efficiency of …

The effect of preorganized versus undefined charge display on the cellular uptake of cationic
cell‐penetrating peptides (CPPs) was investigated by comparing conformationally well …

Live‐cell delivery of a fully synthetic protein having selectivity towards a particular target is a
promising approach with potential applications for basic research and therapeutics. Cell …

Many cell‐penetrating peptides (CPPs) fold at cell surfaces, adopting α‐or β‐structure that
enable their intracellular transport. However, the same structural folds that facilitate cellular …

Proteins and other macromolecules can be delivered into live cells by noninvasive
techniques using cell‐penetrating peptides. These peptides are easily synthesised by solid …