Membraneless organelles in health and disease: exploring the molecular basis, physiological roles and pathological implications
Y Li, Y Liu, XY Yu, Y Xu, X Pan, Y Sun… - … and Targeted Therapy, 2024 - nature.com
Once considered unconventional cellular structures, membraneless organelles (MLOs),
cellular substructures involved in biological processes or pathways under physiological …
cellular substructures involved in biological processes or pathways under physiological …
Plants use molecular mechanisms mediated by biomolecular condensates to integrate environmental cues with development
This review highlights recent literature on biomolecular condensates in plant development
and discusses challenges for fully dissecting their functional roles. Plant developmental …
and discusses challenges for fully dissecting their functional roles. Plant developmental …
Multi-omics landscape and molecular basis of radiation tolerance in a tardigrade
L Li, Z Ge, S Liu, K Zheng, Y Li, K Chen, Y Fu, X Lei… - Science, 2024 - science.org
Tardigrades are captivating organisms known for their resilience in extreme environments,
including ultra-high-dose radiation, but the underlying mechanisms of this resilience remain …
including ultra-high-dose radiation, but the underlying mechanisms of this resilience remain …
Liquid–liquid phase separation in plants: Advances and perspectives from model species to crops
Q Liu, W Liu, Y Niu, T Wang, J Dong - Plant Communications, 2024 - cell.com
Membraneless biomolecular condensates play important roles in both normal biological
activities and responses to environmental stimuli in living organisms. Liquid‒liquid phase …
activities and responses to environmental stimuli in living organisms. Liquid‒liquid phase …
Cold induction of nuclear FRIGIDA condensation in Arabidopsis
Z Zhang, X Luo, Y Yang, Y He - Nature, 2023 - nature.com
Cold induction of nuclear FRIGIDA condensation in Arabidopsis | Nature Skip to main content
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Thank you for visiting nature.com. You are using a browser version with limited support for …
Recent advances in engineering synthetic biomolecular condensates
L Wan, J Ke, Y Zhu, W Zhang, W Mu - Biotechnology Advances, 2024 - Elsevier
Biomolecular condensates are intriguing entities found within living cells. These structures
possess the ability to selectively concentrate specific components through phase separation …
possess the ability to selectively concentrate specific components through phase separation …
β-synuclein regulates the phase transitions and amyloid conversion of α-synuclein
X Li, L Yu, X Liu, T Shi, Y Zhang, Y **ao… - Nature …, 2024 - nature.com
Parkinson's disease (PD) and Dementia with Lewy Bodies (DLB) are neurodegenerative
disorders characterized by the accumulation of α-synuclein aggregates. α-synuclein forms …
disorders characterized by the accumulation of α-synuclein aggregates. α-synuclein forms …
Coacervate vesicles assembled by liquid–liquid phase separation improve delivery of biopharmaceuticals
P Wen, H Huang, R Zhang, H Zheng, T Liang… - Nature Chemistry, 2025 - nature.com
Vesicles play critical roles in cellular materials storage and signal transportation, even in the
formation of organelles and cells. Natural vesicles are composed of a lipid layer that forms a …
formation of organelles and cells. Natural vesicles are composed of a lipid layer that forms a …
MolPhase, an advanced prediction algorithm for protein phase separation
Q Liang, N Peng, Y **e, N Kumar, W Gao… - The EMBO …, 2024 - embopress.org
We introduce MolPhase, an advanced algorithm for predicting protein phase separation
(PS) behavior that improves accuracy and reliability by utilizing diverse physicochemical …
(PS) behavior that improves accuracy and reliability by utilizing diverse physicochemical …
METTL3/METTL14 maintain human nucleoli integrity by mediating SUV39H1/H2 degradation
Nucleoli are fundamentally essential sites for ribosome biogenesis in cells and formed by
liquid-liquid phase separation (LLPS) for a multilayer condensate structure. How the nucleoli …
liquid-liquid phase separation (LLPS) for a multilayer condensate structure. How the nucleoli …