Origins of specificity in protein-DNA recognition
Specific interactions between proteins and DNA are fundamental to many biological
processes. In this review, we provide a revised view of protein-DNA interactions that …
processes. In this review, we provide a revised view of protein-DNA interactions that …
Engineering extracellular electron transfer pathways of electroactive microorganisms by synthetic biology for energy and chemicals production
J Zhang, F Li, D Liu, Q Liu, H Song - Chemical Society Reviews, 2024 - pubs.rsc.org
The excessive consumption of fossil fuels causes massive emission of CO2, leading to
climate deterioration and environmental pollution. The development of substitutes and …
climate deterioration and environmental pollution. The development of substitutes and …
Protein activity regulation by conformational entropy
SR Tzeng, CG Kalodimos - Nature, 2012 - nature.com
How the interplay between protein structure and internal dynamics regulates protein function
is poorly understood. Often, ligand binding, post-translational modifications and mutations …
is poorly understood. Often, ligand binding, post-translational modifications and mutations …
Diversity, versatility and complexity of bacterial gene regulation mechanisms: opportunities and drawbacks for applications in synthetic biology
I Bervoets, D Charlier - FEMS microbiology reviews, 2019 - academic.oup.com
Gene expression occurs in two essential steps: transcription and translation. In bacteria, the
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …
Accurate FRET measurements within single diffusing biomolecules using alternating-laser excitation
Fluorescence resonance energy transfer (FRET) between a donor (D) and an acceptor (A) at
the single-molecule level currently provides qualitative information about distance, and …
the single-molecule level currently provides qualitative information about distance, and …
PRODORIC: state-of-the-art database of prokaryotic gene regulation
PRODORIC is worldwide one of the largest collections of prokaryotic transcription factor
binding sites from multiple bacterial sources with corresponding interpretation and …
binding sites from multiple bacterial sources with corresponding interpretation and …
cAMP and c-di-GMP synergistically support biofilm maintenance through the direct interaction of their effectors
C Liu, D Sun, J Liu, Y Chen, X Zhou, Y Ru, J Zhu… - Nature …, 2022 - nature.com
Nucleotide second messengers, such as cAMP and c-di-GMP, regulate many physiological
processes in bacteria, including biofilm formation. There is evidence of cross-talk between …
processes in bacteria, including biofilm formation. There is evidence of cross-talk between …
Design, construction and characterization of a set of insulated bacterial promoters
We have generated a series of variable-strength, constitutive, bacterial promoters that act
predictably in different sequence contexts, span two orders of magnitude in strength and …
predictably in different sequence contexts, span two orders of magnitude in strength and …
Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism
Using fluorescence resonance energy transfer to monitor distances within single molecules
of abortively initiating transcription initiation complexes, we show that initial transcription …
of abortively initiating transcription initiation complexes, we show that initial transcription …
Activating transcription in bacteria
Bacteria use a variety of mechanisms to direct RNA polymerase to specific promoters in
order to activate transcription in response to growth signals or environmental cues …
order to activate transcription in response to growth signals or environmental cues …