The development of therapeutic approaches for the induction of robust, long-lasting and
antigen-specific immune tolerance remains an important unmet clinical need for the …

Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

Effective drug delivery requires ample dosing at the target tissue while minimizing negative
side effects. Drug delivery vehicles such as polymeric nanoparticles (NPs) are often …

Acetalated dextran (Ac-DEX) is a tunable acid-labile biopolymer with facile synthesis, aptly
designed for the formulation of microparticles for vaccines and immune modulation …

Nowadays, nanotechnology-based modulation of the immune system is presented as a
cutting-edge strategy, which may lead to significant improvements in the treatment of severe …

The high prevalence and rising incidence of autoimmune diseases have become a
prominent public health issue. Autoimmune disorders result from the immune system …

Also known as electrospray, electrohydrodynamic atomization has been used extensively in
the last 15 years to develop polymer-based particles for drug delivery in cell and animal …

Abstract “Inverse vaccination” refers to antigen-specific tolerogenic immunization treatments
that are capable of inhibiting autoimmune responses. In experimental autoimmune …

Autoimmune disorders are characterized by aberrant T cell and B cell reactivity to the body's
own components, resulting in tissue destruction and organ dysfunction. Autoimmune …

Multiple Sclerosis (MS) is a chronic demyelinating autoimmune disease primarily affecting
young adults. Despite an unclear causal factor, symptoms and pathology arise from the …