A review of neutrophil extracellular traps (NETs) in disease: potential anti-NETs therapeutics

V Mutua, LJ Gershwin - Clinical reviews in allergy & immunology, 2021 - Springer
Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …

NETosis and neutrophil extracellular traps in COVID-19: immunothrombosis and beyond

Y Zhu, X Chen, X Liu - Frontiers in Immunology, 2022 - frontiersin.org
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …

[HTML][HTML] Z-form extracellular DNA is a structural component of the bacterial biofilm matrix

JR Buzzo, A Devaraj, ES Gloag, JA Jurcisek… - Cell, 2021 - cell.com
Biofilms are community architectures adopted by bacteria inclusive of a self-formed
extracellular matrix that protects resident bacteria from diverse environmental stresses and …

The vitals of NETs

C Tan, M Aziz, P Wang - Journal of leukocyte biology, 2021 - academic.oup.com
Neutrophils produce neutrophil extracellular traps (NETs) by expelling their extracellular
chromatin embedded with citrullinated histone H3, myeloperoxidase, and other intracellular …

Eosinophil extracellular traps drive asthma progression through neuro-immune signals

Y Lu, Y Huang, J Li, J Huang, L Zhang, J Feng, J Li… - Nature Cell …, 2021 - nature.com
Eosinophilic inflammation is a feature of allergic asthma. Despite mounting evidence
showing that chromatin filaments released from neutrophils mediate various diseases, the …

Molecular mechanisms and therapeutic target of NETosis in diseases

J Huang, W Hong, M Wan, L Zheng - MedComm, 2022 - Wiley Online Library
Evidence shows that neutrophils can protect the host against pathogens in multiple ways,
including the formation and release of neutrophil extracellular traps (NETs). NETs are web …

Acute bacterial meningitis

EC Wall, JM Chan, E Gil… - Current opinion in …, 2021 - journals.lww.com
Acute bacterial meningitis : Current Opinion in Neurology Acute bacterial meningitis :
Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe Get new …

The brain entangled: the contribution of neutrophil extracellular traps to the diseases of the central nervous system

A Manda-Handzlik, U Demkow - Cells, 2019 - mdpi.com
Under normal conditions, neutrophils are restricted from trafficking into the brain
parenchyma and cerebrospinal fluid by the presence of the brain–blood barrier (BBB). Yet …

Community-acquired bacterial meningitis

D van de Beek, MC Brouwer, U Koedel, EC Wall - The Lancet, 2021 - thelancet.com
Progress has been made in the prevention and treatment of community-acquired bacterial
meningitis during the past three decades but the burden of the disease remains high …

Blood-brain crosstalk: the roles of neutrophils, platelets, and neutrophil extracellular traps in neuropathologies

ML Chou, AO Babamale, TL Walker, F Cognasse… - Trends in …, 2023 - cell.com
Systemic inflammation, neurovascular dysfunction, and coagulopathy often occur
concurrently in neuropathologies. Neutrophils and platelets have crucial synergistic roles in …