Adulteration in food has been a concern since the beginning of civilization, as it not only
decreases the quality of food products but also results in a number of ill effects on health …

Under favorable conditions DNA can survive for thousands of years in the remains of dead
organisms. The DNA extracted from such remains is invariably degraded to a small average …

During the last glacial–interglacial cycle, Arctic biotas experienced substantial climatic
changes, yet the nature, extent and rate of their responses are not fully understood …

To date, the only Neandertal genome that has been sequenced to high quality is from an
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …

We assembled genome-wide data from 16 prehistoric Africans. We show that the anciently
divergent lineage that comprises the primary ancestry of the southern African San had a …

It has been shown that Neanderthals contributed genetically to modern humans outside
Africa 47,000–65,000 years ago. Here we analyse the genomes of a Neanderthal and a …

Although an inverse relationship is expected in ancient DNA samples between the number
of surviving DNA fragments and their length, ancient DNA sequencing libraries are strikingly …

The invention and development of next or second generation sequencing methods has
resulted in a dramatic transformation of ancient DNA research and allowed shotgun …

Due to the increasing throughput of current DNA sequencing instruments, sample
multiplexing is necessary for making economical use of available sequencing capacities. A …

Using DNA extracted from a finger bone found in Denisova Cave in southern Siberia, we
have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This …