Super-resolution microscopy (SRM) bypasses the diffraction limit, a physical barrier that
restricts the optical resolution to roughly 250 nm and was previously thought to be …

Fluorescence nanoscopy uniquely combines minimally invasive optical access to the
internal nanoscale structure and dynamics of cells and tissues with molecular detection …

Stress fibers and focal adhesions are complex protein arrays that produce, transmit and
sense mechanical tension. Evidence accumulated over many years led to the conclusion …

Simple Summary The cytoskeleton is a network of protein fibres within cells that provide
structure and support intracellular transport. Focal adhesions are protein complexes …

Cellular mechanisms underlying the development of left–right asymmetry in tissues and
embryos remain obscure. Here, the development of a chiral pattern of actomyosin was …

Fluorescence microscopy has become a ubiquitous method to observe the location of
specific molecular components within cells. However, the resolution of light microscopy is …

Three-dimensional structured illumination microscopy (3D-SIM) is a versatile and accessible
method for super-resolution fluorescence imaging, but generating high-quality data is …

T lymphocytes use surface α β T-cell receptors (TCRs) to recognize peptides bound to MHC
molecules (pMHCs) on antigen-presenting cells (APCs). How the exquisite specificity of high …

Contractile actomyosin bundles, stress fibers, govern key cellular processes including
migration, adhesion, and mechanosensing. Stress fibers are thus critical for developmental …

Although myosin II filaments are known to exist in non-muscle cells,, their dynamics and
organization are incompletely understood. Here, we combined structured illumination …