Liquid domains in model lipid bilayers are frequently studied as models of raft domains in
cell plasma membranes. Micron-scale liquid domains are easily produced in vesicles …

Elementary mode analysis is a useful metabolic pathway analysis tool to identify the
structure of a metabolic network that links the cellular phenotype to the corresponding …

Constraint-based reconstruction and analysis (COBRA) provides a molecular mechanistic
framework for integrative analysis of experimental molecular systems biology data and …

Near equilibrium, small current fluctuations are described by a Gaussian distribution with a
linear-response variance regulated by the dissipation. Here, we demonstrate that dissipation …

This paper describes a free energy principle that tries to explain the ability of biological
systems to resist a natural tendency to disorder. It appeals to circular causality of the sort …

At the inception of human brain map**, two principles of functional anatomy underwrote
most conceptions—and analyses—of distributed brain responses: namely, functional …

We build a rigorous nonequilibrium thermodynamic description for open chemical reaction
networks of elementary reactions. Their dynamics is described by deterministic rate …

Cells are the basic units of all living matter which harness the flow of energy to drive the
processes of life. While the biochemical networks involved in energy transduction are well …

Acetogenic bacteria can convert waste gases into fuels and chemicals. Design of
bioprocesses for waste carbon valorization requires quantification of steady-state carbon …

We lay the foundation of a circuit theory for chemical reaction networks. Chemical reactions
are grouped into chemical modules solely characterized by their current-concentration …