1, 2, 3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships
Z Xu, SJ Zhao, Y Liu - European journal of medicinal chemistry, 2019 - Elsevier
Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …
resistance associated with the currently used anticancer agents create an urgent need to …
Recent advances (2015–2016) in anticancer hybrids
In spite of the development of a large number of novel anticancer drugs over the years,
Cancer remains as a prominent cause of death, worldwide. Numerous drugs that are …
Cancer remains as a prominent cause of death, worldwide. Numerous drugs that are …
1, 2, 3-Triazole-containing compounds as anti–lung cancer agents: Current developments, mechanisms of action, and structure–activity relationship
T Liang, X Sun, W Li, G Hou, F Gao - Frontiers in pharmacology, 2021 - frontiersin.org
Lung cancer is the most common malignancy and leads to around one-quarter of all cancer
deaths. Great advances have been achieved in the treatment of lung cancer with novel …
deaths. Great advances have been achieved in the treatment of lung cancer with novel …
Dearomatization‐Rearomatization Reaction of Metal‐Polarized Aza‐ortho‐Quinone Methides
BC Wang, L Rao, KX Fang, BL Qu, FY **ong… - Angewandte …, 2023 - Wiley Online Library
Metal‐polarized aza‐ortho‐quinone methides (aza‐o‐QMs) are a unique and efficient
handle for azaheterocycle synthesis. Despite great achievements, the potential of these …
handle for azaheterocycle synthesis. Despite great achievements, the potential of these …
Recent advances in synthesis and medicinal chemistry of benzodiazepines
Benzodiazepines (BZDs) represent a diverse class of bicyclic heterocyclic molecules. In the
last few years, benzodiazepines have emerged as potential therapeutic agents. As a result …
last few years, benzodiazepines have emerged as potential therapeutic agents. As a result …
New benzothiazole hybrids as potential VEGFR-2 inhibitors: design, synthesis, anticancer evaluation, and in silico study
A new series of 2-aminobenzothiazole hybrids linked to thiazolidine-2, 4-dione 4a–e, 1, 3, 4-
thiadiazole aryl urea 6a–d, and cyanothiouracil moieties 8a–d was synthesised. The in vitro …
thiadiazole aryl urea 6a–d, and cyanothiouracil moieties 8a–d was synthesised. The in vitro …
Design, synthesis, biological evaluation and molecular docking of new uracil analogs-1, 2, 4-oxadiazole hybrids as potential anticancer agents
A new series of uracil analogues-1, 2, 4-oxadiazole hybrid derivatives were synthesized by
a new, simple, and efficient method using for the first time HAP-SO 3 H as an heterogenous …
a new, simple, and efficient method using for the first time HAP-SO 3 H as an heterogenous …
Design, synthesis, biological evaluation and molecular docking of new 1, 3, 4-oxadiazole homonucleosides and their double-headed analogs as antitumor agents
A novel series of homonucleosides and their double-headed analogs containing
theophylline, 1, 3, 4-oxadiazole, and variant nucleobases was designed and synthesized …
theophylline, 1, 3, 4-oxadiazole, and variant nucleobases was designed and synthesized …
Synthesis and biological evaluation of morpholines linked coumarin–triazole hybrids as anticancer agents
A series of novel morpholines linked coumarin–triazole hybrids (6a–6v) has been
synthesized and evaluated for their anti‐proliferative potential on a panel of five human …
synthesized and evaluated for their anti‐proliferative potential on a panel of five human …
New (E)-1-alkyl-1H-benzo [d] imidazol-2-yl) methylene) indolin-2-ones: Synthesis, in vitro cytotoxicity evaluation and apoptosis inducing studies
A new series of (E)-benzo [d] imidazol-2-yl) methylene) indolin-2-one derivatives has been
synthesized and evaluated for their in vitro cytotoxic activity against a panel of selected …
synthesized and evaluated for their in vitro cytotoxic activity against a panel of selected …