What causes steroid cataracts? A review of steroid‐induced posterior subcapsular cataracts

AI Jobling, RC Augusteyn - Clinical and experimental …, 2002‏ - Wiley Online Library
Prolonged use of glucocorticoids is a significant risk factor for the development of posterior
subcapsular cataract. This places restrictions on the use of glucocorticoids in the treatment …

Rethinking cystic fibrosis pathology: the critical role of abnormal reduced glutathione (GSH) transport caused by CFTR mutation

VM Hudson - Free radical biology and medicine, 2001‏ - Elsevier
Though the cause of cystic fibrosis (CF) pathology is understood to be the mutation of the
CFTR protein, it has been difficult to trace the exact mechanisms by which the pathology …

Influence of postnatally administered glucocorticoids on rat lung growth

SA Tschanz, BM Damke, PH Burri - Neonatology, 1995‏ - karger.com
Postnatal formation of alveoli can be largely prevented by glucocorticoid treatment, which
accelerates alveolar wall thinning and inhibits outgrowth of new interalveolar septa. Since a …

The effectiveness and side effects of dexamethasone in preterm infants with bronchopulmonary dysplasia

PC Ng - Archives of Disease in Childhood, 1993‏ - pmc.ncbi.nlm.nih.gov
The incidence of bronchopulmonary dysplasia (BPD) among ventilated infants is estimated
to be between 4 and 40% depending on gesta-tion but undoubtedly the highest incidence …

The compromised intra‐uterine environment: implications for future lung health

R Harding, ML Cock, S Louey, BJ Joyce… - Clinical and …, 2000‏ - Wiley Online Library
Epidemiological studies of infants, children and adults indicate that prenatal compromises
that restrict fetal growth and cause low birthweight increase the risk of respiratory …

Gill protein turnover: costs of adaptation

AR Lyndon, DF Houlihan - … Biochemistry and Physiology Part A: Molecular …, 1998‏ - Elsevier
Measurements of gill protein synthesis, and hence turnover, were greatly facilitated over the
last decade by the application of “flooding dose” methodology to non-mammalian species …

Effect of glutamine supplementation of the diet on tissue protein synthesis rate of glucocorticoid-treated rats

JJ Boza, M Turini, D Moënnoz, F Montigon, J Vuichoud… - Nutrition, 2001‏ - Elsevier
Although glutamine status in the critically ill patient can be improved by nutritional means,
the most effective way of effecting such supplementation has received little attention. We …

New insights into the pathogenesis of cystic fibrosis: pivotal role of glutathione system dysfunction and implications for therapy

VM Hudson - Treatments in respiratory medicine, 2004‏ - Springer
The cystic fibrosis transmembrane regulator (CFTR) should no longer be viewed primarily as
a 'chloride channel'but recognized as a channel that also controls the efflux of other …

Dexamethasone inhibits small intestinal growth via increased protein catabolism in neonatal pigs

DG Burrin, TJ Wester, TA Davis… - American Journal of …, 1999‏ - journals.physiology.org
Our objective was to determine how dexamethasone (Dex) affects gastrointestinal protein
metabolism and growth in neonatal pigs. Two-day-old pigs were given daily subcutaneous …

Measurement of pulmonary status and surfactant protein levels during dexamethasone treatment of neonatal respiratory distress syndrome.

JY Wang, TF Yeh, YC Lin, K Miyamura, U Holmskov… - Thorax, 1996‏ - thorax.bmj.com
BACKGROUND: Early postnatal use of dexamethasone in infants with respiratory distress
syndrome (RDS) has been shown effectively to improve pulmonary status and to allow early …