The primary role of fibrinogen-related proteins in invertebrates is defense, not coagulation

PC Hanington, SM Zhang - Journal of innate immunity, 2010 - karger.com
In vertebrates, the conversion of fibrinogen into fibrin is an essential process that underlies
the establishment of the supporting protein framework required for coagulation. In …

Invertebrate immune diversity

J Ghosh, CM Lun, AJ Majeske, S Sacchi… - Developmental & …, 2011 - Elsevier
The arms race between hosts and pathogens (and other non-self) drives the molecular
diversification of immune response genes in the host. Over long periods of evolutionary time …

Whole genome analysis of a schistosomiasis-transmitting freshwater snail

CM Adema, LDW Hillier, CS Jones, ES Loker… - Nature …, 2017 - nature.com
Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma
mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global …

Immunity in molluscs: recognition and effector mechanisms, with a focus on bivalvia

M Gerdol, M Gomez-Chiarri, MG Castillo… - Advances in …, 2018 - Springer
The study of molluscan immune systems, in particular those of bivalve molluscs (eg, clams,
oysters, scallops, mussels), has experienced great growth in recent decades, mainly due to …

The C1q domain containing proteins of the Mediterranean mussel Mytilus galloprovincialis: a widespread and diverse family of immune-related molecules

M Gerdol, C Manfrin, G De Moro, A Figueras… - Developmental & …, 2011 - Elsevier
The key component of the classical complement pathway C1q is regarded as a major
connecting link between innate and acquired immunity due to the highly adaptive binding …

Role for a somatically diversified lectin in resistance of an invertebrate to parasite infection

PC Hanington, MA Forys, JW Dragoo… - Proceedings of the …, 2010 - National Acad Sciences
Invertebrates lack adaptive immune systems homologous to those of vertebrates, yet it is
becoming increasingly clear that they can produce diversified antigen recognition …

Advances in gastropod immunity from the study of the interaction between the snail Biomphalaria glabrata and its parasites: A review of research progress over the …

C Coustau, B Gourbal, D Duval, TP Yoshino… - Fish & shellfish …, 2015 - Elsevier
This review summarizes the research progress made over the past decade in the field of
gastropod immunity resulting from investigations of the interaction between the snail …

Gastropod immunobiology

ES Loker - Adv Exp Med Biol, 2010 - Springer
Over their 500 million year history, gastropods have radiated into marine, freshwater and
terrestrial environments and adopted life styles ranging from herbivory to carnivory to …

A large repertoire of parasite epitopes matched by a large repertoire of host immune receptors in an invertebrate host/parasite model

Y Moné, B Gourbal, D Duval… - PLOS neglected …, 2010 - journals.plos.org
For many decades, invertebrate immunity was believed to be non-adaptive, poorly specific,
relying exclusively on sometimes multiple but germ-line encoded innate receptors and …

Transcriptome profiling of Lymnaea stagnalis (Gastropoda) for ecoimmunological research

O Seppälä, JC Walser, T Cereghetti, K Seppälä, T Salo… - BMC genomics, 2021 - Springer
Background Host immune function can contribute to numerous ecological/evolutionary
processes. Ecoimmunological studies, however, typically use one/few phenotypic immune …