Anastomotic leakage is a potentially severe complication occurring after colorectal surgery
and can lead to increased morbidity and mortality, permanent stoma formation, and cancer …

CAR T cell-based therapies have revolutionized the treatment of hematological
malignancies such as leukemia and lymphoma within the last years. In contrast to the …

This selection from the NCCN Guidelines for Rectal Cancer focuses on management of
malignant polyps and resectable nonmetastatic rectal cancer because important updates …

The determination of an optimal treatment plan for an individual patient with rectal cancer is
a complex process. In addition to decisions relating to the intent of rectal cancer surgery (ie …

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Rectal Cancer
address diagnosis, staging, surgical management, perioperative treatment, management of …

PURPOSE In the multicenter, open-label, phase III FOWARC trial, modified infusional
fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) plus radiotherapy resulted in a higher …

Purpose This guideline reviews the evidence and provides recommendations for the
indications and appropriate technique and dose of neoadjuvant radiation therapy (RT) in the …

Despite progressive improvements in the management of patients with locoregionally
confined, advanced-stage solid tumours, distant metastasis remains a very common—and …

Anastomotic leakage (AL) remains one of the most severe complications following colorectal
cancer (CRC) surgery. Indeed, leaks that may occur after any type of intestinal anastomosis …

Simple Summary The management of rectal cancer has become increasingly more complex.
Over the recent year, the use of chemotherapy and radiation before surgical intervention has …