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Discovering riboswitches: the past and the future
Riboswitches are structured noncoding RNA domains used by many bacteria to monitor the
concentrations of target ligands and regulate gene expression accordingly. In the past 20 …
concentrations of target ligands and regulate gene expression accordingly. In the past 20 …
Riboswitches as therapeutic targets: promise of a new era of antibiotics
Introduction The growth of antibiotic resistance among bacterial pathogens is an impending
global threat that can only be averted through the development of novel antibacterial drugs …
global threat that can only be averted through the development of novel antibacterial drugs …
A sensitive and scalable fluorescence anisotropy single stranded RNA targeting approach for monitoring riboswitch conformational states
The capacity of riboswitches to undergo conformational changes in response to binding their
native ligands is closely tied to their functional roles and is an attractive target for …
native ligands is closely tied to their functional roles and is an attractive target for …
Riboswitch mechanisms: new tricks for an old dog
Discovered almost twenty years ago, riboswitches turned out to be one of the most common
regulatory systems in bacteria, with representatives found in eukaryotes and archaea. Unlike …
regulatory systems in bacteria, with representatives found in eukaryotes and archaea. Unlike …
Transcriptional pause extension benefits the stand-by rather than catch-up Rho-dependent termination
Transcriptional pause is essential for all types of termination. In this single-molecule study
on bacterial Rho factor-dependent terminators, we confirm that the three Rho-dependent …
on bacterial Rho factor-dependent terminators, we confirm that the three Rho-dependent …
Crystal structure of Escherichia coli thiamine pyrophosphate-sensing riboswitch in the apo state
The thiamine pyrophosphate (TPP)-sensing riboswitch is one of the earliest discovered and
most widespread riboswitches. Numerous structural studies have been reported for this …
most widespread riboswitches. Numerous structural studies have been reported for this …
Direct and indirect control of Rho-dependent transcription termination by the Escherichia coli lysC riboswitch
Bacterial riboswitches are molecular structures that play a crucial role in controlling gene
expression to maintain cellular balance. The Escherichia coli lysC riboswitch has been …
expression to maintain cellular balance. The Escherichia coli lysC riboswitch has been …
RNA cis-regulators are important for Streptococcus pneumoniae in vivo success
Bacteria have evolved complex transcriptional regulatory networks, as well as many diverse
regulatory strategies at the RNA level, to enable more efficient use of metabolic resources …
regulatory strategies at the RNA level, to enable more efficient use of metabolic resources …
A methodology for the selection and characterization of riboflavin-overproducing Weissella cibaria strains after treatment with roseoflavin
I Diez-Ozaeta, L Martín-Loarte, ML Mohedano… - Frontiers in …, 2023 - frontiersin.org
Fermentative processes by lactic acid bacteria can produce metabolites of interest to the
health and food industries. Two examples are the production of B-group vitamins, and of …
health and food industries. Two examples are the production of B-group vitamins, and of …
Riboregulation in bacteria: From general principles to novel mechanisms of the trp attenuator and its sRNA and peptide products
E Evguenieva‐Hackenberg - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Gene expression strategies ensuring bacterial survival and competitiveness rely on cis‐and
trans‐acting RNA‐regulators (riboregulators). Among the cis‐acting riboregulators are …
trans‐acting RNA‐regulators (riboregulators). Among the cis‐acting riboregulators are …