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Paving the way to single-molecule protein sequencing
Proteins are major building blocks of life. The protein content of a cell and an organism
provides key information for the understanding of biological processes and disease. Despite …
provides key information for the understanding of biological processes and disease. Despite …
Recent progress in solid‐state nanopores
K Lee, KB Park, HJ Kim, JS Yu, H Chae… - Advanced …, 2018 - Wiley Online Library
The solid‐state nanopore has attracted much attention as a next‐generation DNA
sequencing tool or a single‐molecule biosensor platform with its high sensitivity of …
sequencing tool or a single‐molecule biosensor platform with its high sensitivity of …
Identification of single amino acid differences in uniformly charged homopolymeric peptides with aerolysin nanopore
There are still unmet needs in finding new technologies for biomedical diagnostic and
industrial applications. A technology allowing the analysis of size and sequence of short …
industrial applications. A technology allowing the analysis of size and sequence of short …
Electro-osmotic capture and ionic discrimination of peptide and protein biomarkers with FraC nanopores
Biological nanopores are nanoscale sensors employed for high-throughput, low-cost, and
long read-length DNA sequencing applications. The analysis and sequencing of proteins …
long read-length DNA sequencing applications. The analysis and sequencing of proteins …
Single-molecule sensing using nanopores in two-dimensional transition metal carbide (MXene) membranes
Label-free nanopore technology for sequencing biopolymers such as DNA and RNA could
potentially replace existing methods if improvements in cost, speed, and accuracy are …
potentially replace existing methods if improvements in cost, speed, and accuracy are …
Nanopore-based measurements of protein size, fluctuations, and conformational changes
Proteins are structurally dynamic macromolecules, and it is challenging to quantify the
conformational properties of their native state in solution. Nanopores can be efficient tools to …
conformational properties of their native state in solution. Nanopores can be efficient tools to …
Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trap**
Single-molecule techniques are being developed with the exciting prospect of
revolutionizing the healthcare industry by generating vast amounts of genetic and proteomic …
revolutionizing the healthcare industry by generating vast amounts of genetic and proteomic …
Single-molecule biosensors: Recent advances and applications
Single-molecule biosensors serve the unmet need for real time detection of individual
biological molecules in the molecular crowd with high specificity and accuracy, uncovering …
biological molecules in the molecular crowd with high specificity and accuracy, uncovering …
Membrane protein structure, function, and dynamics: a perspective from experiments and theory
Membrane proteins mediate processes that are fundamental for the flourishing of biological
cells. Membrane-embedded transporters move ions and larger solutes across membranes; …
cells. Membrane-embedded transporters move ions and larger solutes across membranes; …
[HTML][HTML] Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers
The capability to screen a range of proteins at the single-molecule level with enhanced
selectivity in biological fluids has been in part a driving force in develo** future diagnostic …
selectivity in biological fluids has been in part a driving force in develo** future diagnostic …