[HTML][HTML] Solid implantable devices for sustained drug delivery

E Magill, S Demartis, E Gavini, AD Permana… - Advanced Drug Delivery …, 2023 - Elsevier
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …

[HTML][HTML] Long-acting microneedle formulations

LK Vora, AH Sabri, Y Naser, A Himawan… - Advanced Drug Delivery …, 2023 - Elsevier
The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …

Microneedle-based biosensing

LK Vora, AH Sabri, PE McKenna, A Himawan… - Nature Reviews …, 2024 - nature.com
Microneedles (MNs) are microscopic needles that are applied to the skin in a minimally
invasive way to facilitate transdermal drug delivery and/or uptake of interstitial fluid from the …

Recent advancements in microneedle technology for multifaceted biomedical applications

D Kulkarni, F Damiri, S Rojekar, M Zehravi… - Pharmaceutics, 2022 - mdpi.com
Microneedle (MNs) technology is a recent advancement in biomedical science across the
globe. The current limitations of drug delivery, like poor absorption, low bioavailability …

[HTML][HTML] Hollow microneedle assisted intradermal delivery of hypericin lipid nanocapsules with light enabled photodynamic therapy against skin cancer

H Abd-El-Azim, IA Tekko, A Ali, A Ramadan… - Journal of Controlled …, 2022 - Elsevier
Photodynamic therapy (PDT) to manage non-melanoma skin cancers has garnered great
attention over the past few years. Hypericin (Hy) is a potent lipid-soluble photosensitiser with …

Hydrogel-forming microarray patches with cyclodextrin drug reservoirs for long-acting delivery of poorly soluble cabotegravir sodium for HIV Pre-Exposure Prophylaxis

F Volpe-Zanutto, LK Vora, IA Tekko… - Journal of Controlled …, 2022 - Elsevier
Hydrogel-forming microarray patches (HF-MAPs) offer minimally invasive, pain-free and
prolonged drug delivery. These devices are designed to be self-administered and self …

The promise of microneedle technologies for drug delivery

RF Donnelly, MR Prausnitz - Drug Delivery and Translational Research, 2024 - Springer
Microneedle (MN) technologies offer the opportunity to improve patient access and target
delivery of drugs and vaccines to specific tissues. When in the form of skin patches, MNs can …

[HTML][HTML] Lyotropic liquid crystals for parenteral drug delivery

VP Chavda, S Dawre, A Pandya, LK Vora… - Journal of Controlled …, 2022 - Elsevier
The necessity for long-term treatments of chronic diseases has encouraged the
development of novel long-acting parenteral formulations intending to improve drug …

Ring inserts as a useful strategy to prepare tip-loaded microneedles for long-acting drug delivery with application in HIV pre-exposure prophylaxis

AJ Paredes, AD Permana, F Volpe-Zanutto, MN Amir… - Materials & …, 2022 - Elsevier
The role of microneedle array patches (MAPs) and, in particular, dissolving MAPs in
transdermal drug delivery has increased exponentially over the last decade. MAPs are able …

[HTML][HTML] Tip loaded cyclodextrin-carvedilol complexes microarray patches

QK Anjani, AHB Sabri, KA Hamid… - Carbohydrate …, 2023 - Elsevier
Carvedilol, a β-blocker prescribed for chronic heart failure, suffers from poor bioavailability
and rapid first pass metabolism when administered orally. Herein, we present the …