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Plasmodium species: master renovators of their host cells
Plasmodium parasites, the causative agents of malaria, have developed elaborate
strategies that they use to survive and thrive within different intracellular environments …
strategies that they use to survive and thrive within different intracellular environments …
How malaria parasites acquire nutrients from their host
NA Counihan, JK Modak… - Frontiers in Cell and …, 2021 - frontiersin.org
Plasmodium parasites responsible for the disease malaria reside within erythrocytes. Inside
this niche host cell, parasites internalize and digest host hemoglobin to source amino acids …
this niche host cell, parasites internalize and digest host hemoglobin to source amino acids …
A proteomic view of the Plasmodium falciparum life cycle
The completion of the Plasmodium falciparum clone 3D7 genome provides a basis on which
to conduct comparative proteomics studies of this human pathogen. Here, we applied a high …
to conduct comparative proteomics studies of this human pathogen. Here, we applied a high …
Discovery of gene function by expression profiling of the malaria parasite life cycle
The completion of the genome sequence for Plasmodium falciparum, the species
responsible for most malaria human deaths, has the potential to reveal hundreds of new …
responsible for most malaria human deaths, has the potential to reveal hundreds of new …
[HTML][HTML] Malaria parasite clag3 genes determine channel-mediated nutrient uptake by infected red blood cells
W Nguitragool, AAB Bokhari, AD Pillai, K Rayavara… - Cell, 2011 - cell.com
Development of malaria parasites within vertebrate erythrocytes requires nutrient uptake at
the host cell membrane. The plasmodial surface anion channel (PSAC) mediates this …
the host cell membrane. The plasmodial surface anion channel (PSAC) mediates this …
The malaria-infected red blood cell: structural and functional changes
BM Cooke, N Mohandas, RL Coppel - 2001 - Elsevier
The asexual stage of malaria parasites of the genus Plasmodium invade red blood cells of
various species including humans. After parasite invasion, red blood cells progressively …
various species including humans. After parasite invasion, red blood cells progressively …
The pathophysiology of falciparum malaria
IA Clark, WB Cowden - Pharmacology & therapeutics, 2003 - Elsevier
Falciparum malaria is a complex disease with no simple explanation, affecting organs where
the parasite is rare as well as those organs where it is more common. We continue to argue …
the parasite is rare as well as those organs where it is more common. We continue to argue …
Virulence in malaria: an evolutionary viewpoint
MJ Mackinnon, AF Read - Philosophical Transactions of …, 2004 - royalsocietypublishing.org
Malaria parasites cause much morbidity and mortality to their human hosts. From our
evolutionary perspective, this is because virulence is positively associated with parasite …
evolutionary perspective, this is because virulence is positively associated with parasite …
Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate
Plasmodium falciparum parasites, the causative agents of malaria, modify their host
erythrocyte to render them permeable to supplementary nutrient uptake from the plasma and …
erythrocyte to render them permeable to supplementary nutrient uptake from the plasma and …
Widespread functional specialization of Plasmodium falciparum erythrocyte membrane protein 1 family members to bind CD36 analysed across a parasite genome
BA Robinson, TL Welch, JD Smith - Molecular microbiology, 2003 - Wiley Online Library
Plasmodium falciparum‐infected erythrocytes sequester from blood circulation by binding
host endothelium. A large family of variant proteins mediates cytoadherence and their …
host endothelium. A large family of variant proteins mediates cytoadherence and their …