[HTML][HTML] Extracellular vesicle-loaded hydrogels for tissue repair and regeneration

Y Ju, Y Hu, P Yang, X **e, B Fang - Materials Today Bio, 2023 - Elsevier
Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles
secreted by cells that play important biological roles. Mesenchymal stem cells are a class of …

Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Structurally dynamic hydrogels for biomedical applications: pursuing a fine balance between macroscopic stability and microscopic dynamics

K Zhang, Q Feng, Z Fang, L Gu, L Bian - Chemical Reviews, 2021 - ACS Publications
Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …

DNA functional materials assembled from branched DNA: design, synthesis, and applications

Y Dong, C Yao, Y Zhu, L Yang, D Luo… - Chemical Reviews, 2020 - ACS Publications
DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture

YH Peng, SK Hsiao, K Gupta, A Ruland… - Nature …, 2023 - nature.com
Three-dimensional cell and organoid cultures rely on the mechanical support of viscoelastic
matrices. However, commonly used matrix materials lack control over key cell-instructive …

Principles and applications of nucleic acid strand displacement reactions

FC Simmel, B Yurke, HR Singh - Chemical reviews, 2019 - ACS Publications
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …

Acid-resistant and physiological pH-responsive DNA hydrogel composed of A-motif and i-motif toward oral insulin delivery

Y Hu, S Gao, H Lu, JY Ying - Journal of the American Chemical …, 2022 - ACS Publications
An acid-resistant DNA hydrogel that is stable in an extremely acidic environment with pH as
low as 1.2 has not been reported before, largely due to the instability of DNA-hybridized …

Hydrogel-based sensor networks: Compositions, properties, and applications—A review

X Sun, S Agate, KS Salem, L Lucia… - ACS Applied Bio …, 2020 - ACS Publications
Hydrogels are three-dimensional porous polymeric networks prepared by physical or
chemical cross-linking of hydrophilic molecules, which can be made into smart materials …

Zero-order drug delivery: State of the art and future prospects

ML Laracuente, HY Marina, KJ McHugh - Journal of Controlled Release, 2020 - Elsevier
Pharmaceutical drugs are an important part of the global healthcare system, with some
estimates suggesting over 50% of the world's population takes at least one medication per …

Stimuli‐responsive biomolecule‐based hydrogels and their applications

M Vázquez‐González, I Willner - … Chemie International Edition, 2020 - Wiley Online Library
This Review presents polysaccharides, oligosaccharides, nucleic acids, peptides, and
proteins as functional stimuli‐responsive polymer scaffolds that yield hydrogels with …