Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …

Increasing evidence indicates that non-DNA sequence-based epigenetic information can be
inherited across several generations in organisms ranging from yeast to plants to humans …

Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

Amino acid metabolism plays important roles in tumor biology and tumor therapy.
Accumulating evidence has shown that amino acids contribute to tumorigenesis and tumor …

Transgenerational epigenetic inheritance in mammals remains a debated subject. Here, we
demonstrate that DNA methylation of promoter-associated CpG islands (CGIs) can be …

The gut microbiota operates at the interface of host–environment interactions to influence
human homoeostasis and metabolic networks,,–. Environmental factors that unbalance gut …

Abstract Divergent N6-methyladenosine (m6A) modifications are dynamic and reversible
posttranscriptional RNA modifications that are mediated by m6A regulators or m6A RNA …

A severe decline in child births has occurred over the past half century, which will lead to
considerable population declines, particularly in industrialized regions. A crucial question is …

With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …

Epigenetics is closely related to cardiovascular diseases. Genome-wide linkage and
association analyses and candidate gene approaches illustrate the multigenic complexity of …