Human serum albumin (HSA) plays a major role in the transport of metallodrugs, affecting
pharmacokinetics and pharmacodynamics of these molecules. This work highlights the …

Platinum-based anticancer drugs have been at the forefront of cancer chemotherapy, with
cisplatin emerging as a pioneer in the treatment of various malignancies. This review article …

Although important progress has been made, cancer still remains a complex disease to
treat. Serious side effects, the insurgence of resistance and poor selectivity are some of the …

The discovery of the antineoplastic properties of cisplatin in 1965 by Rosenberg and co-
workers, originated a renewed attraction for metal complexes for medicinal applications …

Albumin, as the most abundant plasma protein, plays an integral role in the transport of a
variety of exogenous and endogenous ligands in the bloodstream and extravascular …

Electrospray ionization mass spectrometry (ESI MS) is a powerful investigative tool to
analyze the reactions of metallodrugs with proteins and peptides and characterize the …

Cisplatin and its analogues are widely used as chemotherapeutic agents in clinical practice.
After being intravenously administrated, a substantial amount of platinum will bind with …

Globally, an estimated 9 million deaths per year are caused by human exposure to
environmental pollutants, including toxic metal (loid) species. Since pollution is …

The biophysical study provides a quantitative understanding of biomolecular interaction. The
interaction of protein-nanoparticle has been critically examined using various biophysical …

We herein report the synthesis and multi-technique characterization of [Ru2Cl ((2-
phenylindol-3-yl) glyoxyl-L-leucine-L-phenylalanine) 4], a novel diruthenium (II, III) complex …