Expanding the catalytic landscape of metalloenzymes with lytic polysaccharide monooxygenases
Lytic polysaccharide monooxygenases (LPMOs) have an essential role in global carbon
cycle, industrial biomass processing and microbial pathogenicity by catalysing the oxidative …
cycle, industrial biomass processing and microbial pathogenicity by catalysing the oxidative …
A conserved second sphere residue tunes copper site reactivity in lytic polysaccharide monooxygenases
Lytic polysaccharide monooxygenases (LPMOs) are powerful monocopper enzymes that
can activate strong C–H bonds through a mechanism that remains largely unknown. Herein …
can activate strong C–H bonds through a mechanism that remains largely unknown. Herein …
Reductants fuel lytic polysaccharide monooxygenase activity in a pH‐dependent manner
Polysaccharide‐degrading mono‐copper lytic polysaccharide monooxygenases (LPMOs)
are efficient peroxygenases that require electron donors (reductants) to remain in the active …
are efficient peroxygenases that require electron donors (reductants) to remain in the active …
Insight into the peroxygenase activity of lytic polysaccharide monooxygenases (LPMO): Recent progress and mechanistic understanding
W Gao, H Yin - Chemical Physics Reviews, 2023 - pubs.aip.org
The discovery of lytic polysaccharide monooxygenases (LPMOs) as monocopper enzymes
for the oxidative cleavage of glycosidic bonds in recalcitrant polysaccharides has …
for the oxidative cleavage of glycosidic bonds in recalcitrant polysaccharides has …
On the pH Dependency of the Catalysis by a Lytic Polysaccharide Monooxygenase from the Fungus Trichoderma reesei
Lytic polysaccharide monooxygenases (LPMOs) catalyze the oxidative cleavage of
glycosidic bonds in industrially important polysaccharides like cellulose. The activity of these …
glycosidic bonds in industrially important polysaccharides like cellulose. The activity of these …
LPMO‐like activity of bioinspired copper complexes: from model substrate to extended polysaccharides
R Leblay, R Delgadillo‐Ruíz, C Decroos… - …, 2023 - Wiley Online Library
Polysaccharide oxidative depolymerization is highly desirable to achieve recalcitrant
biomass valorization. Inspired by recently discovered Lytic Polysaccharide …
biomass valorization. Inspired by recently discovered Lytic Polysaccharide …
Integrated Experimental and Theoretical Investigation of Copper Active Site Properties of a Lytic Polysaccharide Monooxygenase from Serratia marcescens
In this paper, we employed a multidisciplinary approach, combining experimental
techniques and density functional theory (DFT) calculations to elucidate key features of the …
techniques and density functional theory (DFT) calculations to elucidate key features of the …
Selective oxidation of active site aromatic residues in engineered Cu proteins
Recent studies have revealed critical roles for the local environments surrounding
metallocofactors, such as the newly identified CuD site in particulate methane …
metallocofactors, such as the newly identified CuD site in particulate methane …