Computer-aided design techniques for flow-based microfluidic lab-on-a-chip systems

X Huang, TY Ho, W Guo, B Li, K Chakrabarty… - ACM Computing …, 2021 - dl.acm.org
As one of the most promising lab-on-a-chip systems, flow-based microfluidic biochips are
being increasingly used for automatically executing various laboratory procedures in biology …

Design automation for continuous-flow microfluidic biochips: A comprehensive review

G Liu, H Huang, Z Chen, H Lin, H Liu, X Huang, W Guo - Integration, 2022 - Elsevier
Continuous-flow microfluidic biochips (CFMBs), also known as lab-on-a-chip platforms, have
attracted considerable attentions in the past two decades and have been widely used in …

Flow-based microfluidic biochips with distributed channel storage: Synthesis, physical design, and wash optimization

X Huang, W Guo, Z Chen, B Li, TY Ho… - IEEE Transactions …, 2021 - ieeexplore.ieee.org
System-architecture design optimization of flow-based microfluidic biochips has been
extensively investigated over the past decade. Most of the prior work, however, is still based …

Columba 2.0: A co-layout synthesis tool for continuous-flow microfluidic biochips

TM Tseng, M Li, DN Freitas, T McAuley… - … on Computer-Aided …, 2017 - ieeexplore.ieee.org
Continuous-flow microfluidic large-scale integration (mLSI) shows increasing importance in
biological/chemical fields, thanks to its advantages in miniaturization and high throughput …

Close-to-optimal placement and routing for continuous-flow microfluidic biochips

A Grimmer, Q Wang, H Yao, TY Ho… - 2017 22nd Asia and …, 2017 - ieeexplore.ieee.org
Continuous-flow microfluidics rapidly evolved in the last decades as a solution to automate
laboratory procedures in molecular biology and biochemistry. Therefore, the physical design …

BigIntegr: One-pass architectural synthesis for continuous-flow microfluidic lab-on-a-chip systems

X Huang, Y Pan, Z Chen, W Guo, R Wille… - 2021 IEEE/ACM …, 2021 - ieeexplore.ieee.org
The emergence of continuous-flow microfluidics has led to a revolution in biochemistry and
biomedicine. On such a microscale lab-on-a-chip system, complex biochemical assays, eg …

Computer-aided design of microfluidic circuits

EE Tsur - Annual review of biomedical engineering, 2020 - annualreviews.org
Microfluidic devices developed over the past decade feature greater intricacy, increased
performance requirements, new materials, and innovative fabrication methods …

Timing-driven flow-channel network construction for continuous-flow microfluidic biochips

X Huang, TY Ho, K Chakrabarty… - IEEE Transactions on …, 2019 - ieeexplore.ieee.org
The emergence of flow-based microfluidic biochips (FBMBs) has increased the automation
level of biochemical procedures, and these lab-on-a-chip devices are now being used for …

Transport or store? Synthesizing flow-based microfluidic biochips using distributed channel storage

C Liu, B Li, H Yao, P Pop, TY Ho… - Proceedings of the 54th …, 2017 - dl.acm.org
Flow-based microfluidic biochips have attracted much attention in the EDA community due
to their miniaturized size and execution efficiency. Previous research, however, still follows …

PACOR: practical control-layer routing flow with length-matching constraint for flow-based microfluidic biochips

H Yao, TY Ho, Y Cai - Proceedings of the 52nd Annual Design …, 2015 - dl.acm.org
In flow-based microfluidic biochips, microvalves on the control layer need to be connected to
control pins via control channels. In application-specific and portable microfluidic devices …