Hypoxia, a hallmark of most solid tumours, is a negative prognostic factor due to its
association with an aggressive tumour phenotype and therapeutic resistance. Given its …

Hypoxia, a condition of insufficient O 2 to support metabolism, occurs when the vascular
supply is interrupted, as in stroke or myocardial infarction, or when a tumor outgrows its …

Purpose Hypoxia is a condition of insufficient oxygen to support metabolism which occurs
when the vascular supply is interrupted, or when a tumour outgrows its vascular supply. It is …

Purpose: Advanced head and neck cancer shows hypoxia that results in biological changes
to make the tumor cells more aggressive and less responsive to treatment resulting in poor …

Purpose Several individual clinical and preclinical studies have shown the possibility of
evaluating tumor hypoxia by using noninvasive positron emission tomography (PET). The …

A tumor‐specific microenvironment is characterized by hypoxia, in which oxygen tension is
considerably lower than in normal tissues. The hypoxic status of various solid tumors has …

Tissue hypoxia results from an inadequate supply of oxygen (O 2) that compromises
biological functions. Structural and functional abnormalities of the tumour vasculature …

PURPOSE: Hypoxia is one of the main causes of the failure to achieve local control using
radiotherapy. This is due to the increased radioresistance of hypoxic cells. 18F …

Cancer cells in hypoxic areas of solid tumors are to a large extent protected against the
action of radiation as well as many chemotherapeutic drugs. There are, however, two …

The hypoxic state in a solid tumor refers to the internal hypoxic environment that appears as
the tumor volume increases (the maximum radius exceeds 180-200 microns). This state can …