Viruses, friends, and foes: The case of Torque Teno Virus and the net state of immunosuppression

N Redondo, D Navarro, JM Aguado… - Transplant Infectious …, 2022 - Wiley Online Library
New reliable biomarkers are needed to improve individual risk assessment for post‐
transplant infection, acute graft rejection and other immune‐related complications after solid …

Integrated immunologic monitoring in solid organ transplantation: the road toward torque Teno virus-guided immunosuppression

P Jaksch, I Görzer, E Puchhammer-Stöckl… - Transplantation, 2022 - journals.lww.com
Potent immunosuppressive drugs have been introduced into clinical care for solid organ
transplant recipients. It is now time to guide these drugs on an individual level to optimize …

Perspective on taxonomic classification of uncultivated viruses

BE Dutilh, A Varsani, Y Tong, P Simmonds… - Current opinion in …, 2021 - Elsevier
Historically, virus taxonomy has been limited to describing viruses that were readily
cultivated in the laboratory or emerging in natural biomes. Metagenomic analyses, single …

The enigmatic roles of Anelloviridae and Redondoviridae in humans

LJ Taylor, EL Keeler, FD Bushman… - Current Opinion in …, 2022 - Elsevier
Anelloviridae and Redondoviridae are virus families with small, circular, single-stranded
DNA genomes that are common components of the human virome. Despite their small …

Anelloviruses versus human immunity: how do we control these viruses?

AL Timmerman, ALM Schönert… - FEMS microbiology …, 2024 - academic.oup.com
One continuous companion and one of the major players in the human blood virome are
members of the Anelloviridae family. Anelloviruses are probably found in all humans …

[HTML][HTML] Validation of plasma Torque Teno viral load applying a CE-certified PCR for risk stratification of rejection and infection post kidney transplantation

I Görzer, F Haupenthal, F Maggi, F Gelas… - Journal of Clinical …, 2023 - Elsevier
Abstract Background Torque Teno virus (TTV) is non-pathogenic, highly prevalent and
reflects the immune status of its host. TTV plasma load was suggested for risk stratification of …

Evolution of anelloviruses from a circovirus-like ancestor through gradual augmentation of the jelly-roll capsid protein

A Butkovic, S Kraberger, Z Smeele, DP Martin… - Virus …, 2023 - academic.oup.com
Anelloviruses are highly prevalent in diverse mammals, including humans, but so far have
not been linked to any disease and are considered to be part of the 'healthy virome'. These …

Gyrovirus: current status and challenge

T Yan, Z Wang, R Li, D Zhang, Y Song… - Frontiers in …, 2024 - frontiersin.org
Gyrovirus (GyV) is small, single-stranded circular DNA viruses that has recently been
assigned to the family Anelloviridae. In the last decade, many GyVs that have an apparent …

Human Anelloviruses: influence of demographic factors, recombination, and worldwide diversity

M Cebriá-Mendoza, B Beamud… - Microbiology …, 2023 - Am Soc Microbiol
Anelloviruses represent the major and most diverse component of the healthy human
virome, referred to as the anellome. In this study, we determined the anellome of 50 blood …

Anelloviridae taxonomy update 2023

A Varsani, S Kraberger, T Opriessnig, F Maggi… - Archives of …, 2023 - Springer
The family Anelloviridae comprises negative single-stranded circular DNA viruses. Within
this family, there are 30 established genera. Anelloviruses in the genus Gyrovirus have been …