Genotype× environment interaction QTL map** in plants: lessons from Arabidopsis

M El-Soda, M Malosetti, BJ Zwaan, M Koornneef… - Trends in plant …, 2014 - cell.com
Plant growth and development are influenced by the genetic composition of the plant (G),
the environment (E), and the interaction between them (G× E). To produce suitable …

Metabolite-based genome-wide association studies in plants

J Luo - Current opinion in plant biology, 2015 - Elsevier
Highlights•mGWAS in plants benefit from huge diversity of the plant metabolome.•mGWAS is
powerful in dissecting the genetic basis of the plant metabolome.•mGWAS provides an …

Genome-wide association analyses provide genetic and biochemical insights into natural variation in rice metabolism

W Chen, Y Gao, W **e, L Gong, K Lu, W Wang, Y Li… - Nature …, 2014 - nature.com
Plant metabolites are important to world food security in terms of maintaining sustainable
yield and providing food with enriched phytonutrients. Here we report comprehensive …

An InDel in the Promoter of Al-ACTIVATED MALATE TRANSPORTER9 Selected during Tomato Domestication Determines Fruit Malate Contents and Aluminum …

J Ye, X Wang, T Hu, F Zhang, B Wang, C Li… - The Plant …, 2017 - academic.oup.com
Deciphering the mechanism of malate accumulation in plants would contribute to a greater
understanding of plant chemistry, which has implications for improving flavor quality in crop …

Identifying genetic variants underlying phenotypic variation in plants without complete genomes

Y Voichek, D Weigel - Nature genetics, 2020 - nature.com
Structural variants and presence/absence polymorphisms are common in plant genomes,
yet they are routinely overlooked in genome-wide association studies (GWAS). Here, we …

Identification and mode of inheritance of quantitative trait loci for secondary metabolite abundance in tomato

S Alseekh, T Tohge, R Wendenberg, F Scossa… - The Plant …, 2015 - academic.oup.com
A large-scale metabolic quantitative trait loci (mQTL) analysis was performed on the well-
characterized Solanum pennellii introgression lines to investigate the genomic regions …

The genetics of plant metabolism

AR Fernie, T Tohge - Annual Review of Genetics, 2017 - annualreviews.org
Plant metabolic studies have traditionally focused on the role and regulation of the enzymes
catalyzing key reactions within specific pathways. Within the past 20 years, reverse genetic …

Higher-order genetic interactions and their contribution to complex traits

MB Taylor, IM Ehrenreich - Trends in genetics, 2015 - cell.com
The contribution of genetic interactions involving three or more loci to complex traits is poorly
understood. These higher-order genetic interactions (HGIs) are difficult to detect in genetic …

Explaining additional genetic variation in complex traits

MR Robinson, NR Wray, PM Visscher - Trends in Genetics, 2014 - cell.com
Genome-wide association studies (GWAS) have provided valuable insights into the genetic
basis of complex traits, discovering> 6000 variants associated with> 500 quantitative traits …

The role of mitochondria in plant development and stress tolerance

KL Liberatore, S Dukowic-Schulze, ME Miller… - Free Radical Biology …, 2016 - Elsevier
Eukaryotic cells require orchestrated communication between nuclear and organellar
genomes, perturbations in which are linked to stress response and disease in both animals …