Epigenetics has enriched human disease studies by adding new interpretations to disease
features that cannot be explained by genetic and environmental factors. However …

For over a century, the Michaelis–Menten (MM) rate law has been used to describe the rates
of enzyme-catalyzed reactions and gene expression. Despite the ubiquity of the MM rate …

A key goal of chemistry is to develop synthetic systems that mimic biology, such as self-
assembling, self-replicating models of minimal life forms. Oscillations are often observed in …

The network of proteins that orchestrate the distribution of cholesterol among cellular
organelles is not fully characterized. We previously proposed that oxysterol‐binding protein …

The GTPase Cdc42 regulates polarized growth in most eukaryotes. In the bipolar yeast
Schizosaccharomyces pombe, Cdc42 activation cycles periodically at sites of polarized …

Stress granules (SGs) are formed in the cytosol as an acute response to environmental cues
and activation of the integrated stress response (ISR), a central signaling pathway …

Synthetic microbial consortia have an advantage over isogenic synthetic microbes because
they can apportion biochemical and regulatory tasks among the strains. However, it is …

One of the grand challenges in contemporary systems chemistry research is to mimic life-like
functions using simple synthetic molecular networks. This is particularly true for systems that …

Synthetic gene circuits allow us to govern cell behavior in a programmable manner, which is
central to almost any application aiming to harness engineered living cells for user-defined …

Clostridia are interesting candidates for biotechnological applications due to their diverse
and unique metabolic abilities. Particularly in continuous fermentation processes …