Normal haemostasis depends on an intricate balance between mechanisms of bleeding and
mechanisms of thrombosis, and this balance can be altered after traumatic brain injury (TBI) …

Traumatic brain injury (TBI)–induced coagulopathy is a common and well-recognized risk for
poor clinical outcomes, but its pathogenesis remains poorly understood, and treatment …

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …

Lipid peroxidation can be broadly defined as the process of inserting a hydroperoxy group
into a lipid. Polyunsaturated fatty acids present in the phospholipids are often the targets for …

The optimal management of mild traumatic brain injury (TBI) patients with injuries identified
by computed tomography (CT) brain scan is unclear. Some guidelines recommend hospital …

BACKGROUND Anticoagulants and prescription antiplatelet (ACAP) agents widely used by
older adults have the potential to adversely affect traumatic brain injury (TBI) outcomes. We …

Traumatic brain injury (TBI) is a growing global problem, which is responsible for a
substantial burden of disability and death, and which generates substantial healthcare costs …

The objective of this systematic review and meta-analysis is to evaluate whether the pre-
injury use of antiplatelet therapy (APT) is associated with increased risk of traumatic …

A unique coagulopathy often manifests following traumatic brain injury, leading the clinician
down a difficult decision path on appropriate prophylaxis and therapy. Conventional …