[HTML][HTML] Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies

SV Bhujbal, B Mitra, U Jain, Y Gong, A Agrawal… - … Pharmaceutica Sinica B, 2021 - Elsevier
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …

Current and emerging applications of 3D printing in medicine

CY Liaw, M Guvendiren - Biofabrication, 2017 - iopscience.iop.org
Abstract Three-dimensional (3D) printing enables the production of anatomically matched
and patient-specific devices and constructs with high tunability and complexity. It also allows …

Tinkering with mechanochemical tools for scale up

JF Reynes, V Isoni, F García - … Chemie International Edition, 2023 - Wiley Online Library
Mechanochemistry provides an environmentally benign platform to develop more
sustainable chemical processes by limiting raw materials, energy use, and waste generation …

Coupling 3D printing with hot-melt extrusion to produce controlled-release tablets

J Zhang, X Feng, H Patil, RV Tiwari… - International journal of …, 2017 - Elsevier
The main objective of this work was to explore the potential of coupling fused deposition
modeling in three-dimensional (3D) printing with hot-melt extrusion (HME) technology to …

M3DISEEN: A novel machine learning approach for predicting the 3D printability of medicines

M Elbadawi, BM Castro, FKH Gavins, JJ Ong… - International Journal of …, 2020 - Elsevier
Artificial intelligence (AI) has the potential to reshape pharmaceutical formulation
development through its ability to analyze and continuously monitor large datasets. Fused …

Changes in conformation and quality of vegetable protein during texturization process by extrusion

J Zhang, L Liu, H Liu, A Yoon, SSH Rizvi… - Critical reviews in food …, 2019 - Taylor & Francis
Abstract Texturized Vegetable Protein (TVP), as meat analogs, has garnered attention due
to the nutritional advantages it offers over conventional animal proteins. During the extrusion …

[HTML][HTML] Novel gastroretentive floating pulsatile drug delivery system produced via hot-melt extrusion and fused deposition modeling 3D printing

N Reddy Dumpa, S Bandari, M A. Repka - Pharmaceutics, 2020 - mdpi.com
This study was performed to develop novel core-shell gastroretentive floating pulsatile drug
delivery systems using a hot-melt extrusion-paired fused deposition modeling (FDM) 3D …

Coupling hot melt extrusion and fused deposition modeling: Critical properties for successful performance

S Bandari, D Nyavanandi, N Dumpa… - Advanced drug delivery …, 2021 - Elsevier
Interest in 3D printing for pharmaceutical applications has increased in recent years.
Compared to other 3D printing techniques, hot melt extrusion (HME)-based fused deposition …

Melt extrusion with poorly soluble drugs–An integrated review

MA Repka, S Bandari, VR Kallakunta, AQ Vo… - International journal of …, 2018 - Elsevier
Over the last few decades, hot melt extrusion (HME) has emerged as a successful
technology for a broad spectrum of applications in the pharmaceutical industry. As indicated …

A systematic and robust assessment of hot-melt extrusion-based amorphous solid dispersions: Theoretical prediction to practical implementation

A Alzahrani, D Nyavanandi, P Mandati… - International journal of …, 2022 - Elsevier
Amorphous solid dispersions (ASDs) have gained attention as a formulation strategy in
recent years, with the potential to improve the apparent solubility and, hence, the oral …