Antiviral effects of phytochemicals against severe acute respiratory syndrome coronavirus 2 and their mechanisms of action: A review
The worldwide spreading of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐
2) has posed a serious threat to health, economic, environmental, and social aspects of …
2) has posed a serious threat to health, economic, environmental, and social aspects of …
In silico bioprospecting of taraxerol as a main protease inhibitor of SARS-CoV-2 to develop therapy against COVID-19
COVID-19 was caused by a novel coronavirus known as SARS-CoV-2. The COVID-19
disease outbreak has been avowed as a global pandemic by the World Health Organization …
disease outbreak has been avowed as a global pandemic by the World Health Organization …
Repurposing clinically available drugs and therapies for pathogenic targets to combat SARS‐CoV‐2
Abstract The coronavirus disease 2019 (COVID‐19) pandemic has affected a large portion
of the global population, both physically and mentally. Current evidence suggests that the …
of the global population, both physically and mentally. Current evidence suggests that the …
Non-nucleotide RNA-dependent RNA polymerase inhibitor that blocks SARS-CoV-2 replication
M Dejmek, E Konkoľová, L Eyer, P Straková… - Viruses, 2021 - mdpi.com
SARS-CoV-2 has caused an extensive pandemic of COVID-19 all around the world. Key
viral enzymes are suitable molecular targets for the development of new antivirals against …
viral enzymes are suitable molecular targets for the development of new antivirals against …
Interference of small compounds and Mg2+ with dsRNA-binding fluorophores compromises the identification of SARS-CoV-2 RdRp inhibitors
S Llanos, B Di Geronimo, E Casajús… - Scientific Reports, 2024 - nature.com
The COVID-19 pandemic highlighted the need for the rapid development of antiviral
therapies. Viral RNA-dependent RNA polymerases (RdRp) are promising targets, and …
therapies. Viral RNA-dependent RNA polymerases (RdRp) are promising targets, and …
SARS-CoV-2 RNA-dependent RNA polymerase as a target for high-throughput drug screening
J Wu, Z Chen, X Han, Q Chen, Y Wang, T Feng - Future Virology, 2023 - Taylor & Francis
The ongoing COVID-19 pandemic caused by the SARS-CoV-2 has necessitated rapid
development of drug screening tools. RNA-dependent RNA polymerase (RdRp) is a …
development of drug screening tools. RNA-dependent RNA polymerase (RdRp) is a …
Lessons learnt from broad-spectrum coronavirus antiviral drug discovery
ABSTRACT Introduction Highly pathogenic coronaviruses (CoVs), such as severe acute
respiratory syndrome CoV (SARS-CoV), Middle East respiratory syndrome CoV (MERS …
respiratory syndrome CoV (SARS-CoV), Middle East respiratory syndrome CoV (MERS …
Phytochemicals of Hibiscus sabdariffa with Therapeutic Potential against SARS-CoV-2: A Molecular Docking Study
In this study, the possible interactions of 17 phytochemicals that were reported as the most
abundant biomolecules of Hibiscus sabdariffa, including many organic acids as well as …
abundant biomolecules of Hibiscus sabdariffa, including many organic acids as well as …
A Comprehensive Review on In Silico-predicted Potential Phytochemicals against SARS-CoV-2: Food for Thought for Researchers
The novel coronavirus disease (COVID-19) emerged in December 2019. It is caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is still existent all over …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is still existent all over …