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Follicle-stimulating hormone signaling in Sertoli cells: a licence to the early stages of spermatogenesis
JM Wang, ZF Li, WX Yang, FQ Tan - Reproductive Biology and …, 2022 - Springer
Follicle-stimulating hormone signaling is essential for the initiation and early stages of
spermatogenesis. Follicle-stimulating hormone receptor is exclusively expressed in Sertoli …
spermatogenesis. Follicle-stimulating hormone receptor is exclusively expressed in Sertoli …
FSH regulates RA signaling to commit spermatogonia into differentiation pathway and meiosis
M Khanehzad, R Abbaszadeh, M Holakuyee… - Reproductive Biology …, 2021 - Springer
Background Spermatogenesis is a complex process that is controlled by interactions
between germ cells and somatic cells. The commitment of undifferentiated spermatogonia to …
between germ cells and somatic cells. The commitment of undifferentiated spermatogonia to …
Single-cell multi-omics sequencing of human spermatogenesis reveals a DNA demethylation event associated with male meiotic recombination
Y Huang, L Li, G An, X Yang, M Cui, X Song, J Lin… - Nature Cell …, 2023 - nature.com
Human spermatogenesis is a highly ordered process; however, the roles of DNA
methylation and chromatin accessibility in this process remain largely unknown. Here by …
methylation and chromatin accessibility in this process remain largely unknown. Here by …
FGF9 promotes mouse spermatogonial stem cell proliferation mediated by p38 MAPK signalling
Objectives Fibroblast growth factor 9 (FGF9) is expressed by somatic cells in the
seminiferous tubules, yet little information exists about its role in regulating spermatogonial …
seminiferous tubules, yet little information exists about its role in regulating spermatogonial …
Sertoli cells-derived exosomal miR-30a-5p regulates ubiquitin E3 ligase Zeb2 to affect the spermatogonial stem cells proliferation and differentiation
B Wang, C Zhai, Y Li, B Ma, Z Li, J Wang - Reproductive Toxicology, 2023 - Elsevier
The role of spermatogonial stem cells (SSCs) is crucial in spermatogenesis, and
extracellular vesicles (EVs) have been the focus of research as an important intercellular …
extracellular vesicles (EVs) have been the focus of research as an important intercellular …
Distinct expression profiles and novel targets of MicroRNAs in human spermatogonia, pachytene spermatocytes, and round spermatids between OA patients and NOA …
C Yao, Q Yuan, M Niu, H Fu, F Zhou, W Zhang… - … Therapy-Nucleic Acids, 2017 - cell.com
Human spermatogenesis includes three main stages, namely, the mitosis of spermatogonia,
meiosis of spermatocytes, and spermiogenesis of spermatids, which are precisely regulated …
meiosis of spermatocytes, and spermiogenesis of spermatids, which are precisely regulated …
Oestrogen in the chick embryo can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex that can support oogenesis
S Guioli, D Zhao, S Nandi, M Clinton… - …, 2020 - journals.biologists.com
In chickens, the embryonic ovary differentiates into two distinct domains before meiosis: a
steroidogenic core (the female medulla), overlain by the germ cell niche (the cortex). The …
steroidogenic core (the female medulla), overlain by the germ cell niche (the cortex). The …
MAPK activation drives male and female mouse teratocarcinomas from late primordial germ cells
E Guida, V Tassinari, A Colopi, F Todaro… - Journal of Cell …, 2022 - journals.biologists.com
Germ cell tumors (GCTs) are rare tumors that can develop in both sexes, peaking in
adolescents. To understand the mechanisms that underlie germ cell transformation, we …
adolescents. To understand the mechanisms that underlie germ cell transformation, we …
VEGFC/VEGFR3 signaling regulates mouse spermatogonial cell proliferation via the activation of AKT/MAPK and cyclin D1 pathway and mediates the apoptosis by …
L Zhao, Z Zhu, C Yao, Y Huang, E Zhi, H Chen, R Tian… - Cell Cycle, 2018 - Taylor & Francis
We have previously shown that the transcript levels of Vegfc and its receptor Vegfr3 were
high in spermatogonia and extremely low in spermatocytes and spermatids. However, it …
high in spermatogonia and extremely low in spermatocytes and spermatids. However, it …
To study the mechanism of Cuscuta chinensis Lam. and Lycium barbarum L. in the treatment of asthenospermia based on network pharmacology
J Wang, B Bao, F Meng, S Deng, H Dai, J Feng… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Cuscuta chinensis Lam. and Lycium barbarum
L.(SC-FL) is a commonly used kidney tonic Chinese medicine combination that is widely …
L.(SC-FL) is a commonly used kidney tonic Chinese medicine combination that is widely …