Diagnosis for latent tuberculosis infection: new alternatives
C Carranza, S Pedraza-Sanchez… - Frontiers in …, 2020 - frontiersin.org
Latent tuberculosis infection (LTBI) is a subclinical mycobacterial infection defined on the
basis of cellular immune response to mycobacterial antigens. The tuberculin skin test (TST) …
basis of cellular immune response to mycobacterial antigens. The tuberculin skin test (TST) …
Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection
Mycobacterium tuberculosis is a leading cause of mortality worldwide and establishes a
long-lived latent infection in a substantial proportion of the human population. Multiple lines …
long-lived latent infection in a substantial proportion of the human population. Multiple lines …
[HTML][HTML] A functional role for antibodies in tuberculosis
While a third of the world carries the burden of tuberculosis, disease control has been
hindered by a lack of tools, including a rapid, point-of-care diagnostic and a protective …
hindered by a lack of tools, including a rapid, point-of-care diagnostic and a protective …
Robust IgM responses following intravenous vaccination with Bacille Calmette–Guérin associate with prevention of Mycobacterium tuberculosis infection in …
Abstract Development of an effective tuberculosis (TB) vaccine has suffered from an
incomplete understanding of the correlates of protection against Mycobacterium tuberculosis …
incomplete understanding of the correlates of protection against Mycobacterium tuberculosis …
What have we learnt about BCG vaccination in the last 20 years?
HM Dockrell, SG Smith - Frontiers in immunology, 2017 - frontiersin.org
A number of new tuberculosis (TB) vaccines have been or are entering clinical trials, which
include genetically modified mycobacteria, mycobacterial antigens delivered by viral …
include genetically modified mycobacteria, mycobacterial antigens delivered by viral …
Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease
Our understanding of mechanisms underlying progression from Mycobacterium tuberculosis
infection to pulmonary tuberculosis disease in humans remains limited. To define such …
infection to pulmonary tuberculosis disease in humans remains limited. To define such …
Key advances in vaccine development for tuberculosis—Success and challenges
Breakthrough findings in the clinical and preclinical development of tuberculosis (TB)
vaccines have galvanized the field and suggest, for the first time since the development of …
vaccines have galvanized the field and suggest, for the first time since the development of …
Live-attenuated Mycobacterium tuberculosis vaccine MTBVAC versus BCG in adults and neonates: a randomised controlled, double-blind dose-escalation trial
Background Infants are a key target population for new tuberculosis vaccines. We assessed
the safety and immunogenicity of the live-attenuated Mycobacterium tuberculosis vaccine …
the safety and immunogenicity of the live-attenuated Mycobacterium tuberculosis vaccine …
Accelerating research and development of new vaccines against tuberculosis: a global roadmap
F Cobelens, RK Suri, M Helinski… - The Lancet Infectious …, 2022 - thelancet.com
To eliminate tuberculosis globally, a new, effective, and affordable vaccine is urgently
needed, particularly for use in adults and adolescents in low-income and middle-income …
needed, particularly for use in adults and adolescents in low-income and middle-income …
Moving tuberculosis vaccines from theory to practice
Tuberculosis (TB) vaccine research has reached a unique point in time. Breakthrough
findings in both the basic immunology of Mycobacterium tuberculosis infection and the …
findings in both the basic immunology of Mycobacterium tuberculosis infection and the …