Background Ten years after the first proposal, a consensus definition of healthcare-
associated infection (HCAI) has not been reached, preventing the development of specific …

Purpose To provide guidelines on antimicrobial prophylaxis for adult neutropenic oncology
outpatients and on selection and treatment as outpatients of those with fever and …

Among responders to microbial invasion, neutrophils represent one of the earliest and
perhaps most important factors that contribute to initial host defense. Effective neutrophil …

Neutrophils are the most abundant white blood cells in circulation and constitute up to 60%
of circulating leukocytes. Neutrophils play a significant role in host defense against …

Background Long‐term tunnelled central venous catheters (TCVCs) are increasingly used
when treating oncology patients. Despite international guidelines on sterile insertion …

Goals To assess the type, frequency, severity, and outcome of all infectious episodes in a
pediatric patient cohort with acute lymphoblastic leukemia (ALL) from a single institution …

Gram-negative and gram-positive infections have been considered the most important
causes of morbidity and mortality in patients with leukopenia following chemotherapy …

Febrile neutropenia (FN) is characterized by a decrease in neutrophils number to values
below 500 cells/mm3 and an occurrence of fever higher or similar to38. 3ºC. It commonly …

Neutrophil spontaneous apoptosis, a process crucial for immune regulation, is mainly
controlled by alterations in reactive oxygen species (ROS) and mitochondria integrity …

We hypothesise that treating patients with acute leukaemia in general wards, with proper
hygienic and sanitary practices, would result in the minimum utilisation of resources as …