[HTML][HTML] Pediatric tuberculosis management: a global challenge or breakthrough?

LNF Maphalle, BB Michniak-Kohn, MO Ogunrombi… - Children, 2022 - mdpi.com
Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and
long-lasting solutions as TB is one of the top ten causes of ill health and death in children as …

Application of lipid-based nanocarriers for antitubercular drug delivery: a review

AB Buya, BA Witika, AM Bapolisi, C Mwila… - Pharmaceutics, 2021 - mdpi.com
The antimicrobial drugs currently used for the management of tuberculosis (TB) exhibit poor
bioavailability that necessitates prolonged treatment regimens and high dosing frequency to …

Comparison of different treatments for isoniazid-resistant tuberculosis: an individual patient data meta-analysis

F Fregonese, SD Ahuja, OW Akkerman… - The lancet respiratory …, 2018 - thelancet.com
Background Isoniazid-resistant, rifampicin-susceptible (INH-R) tuberculosis is the most
common form of drug resistance, and is associated with failure, relapse, and acquired …

Counting children with tuberculosis: why numbers matter

JA Seddon, HE Jenkins, L Liu, T Cohen… - … of Tuberculosis and …, 2015 - ingentaconnect.com
In the last 5 years, childhood tuberculosis (TB) has received increasing attention from
international organisations, national TB programmes and academics. For the first time, a …

[HTML][HTML] Prevalence of drug-resistant tuberculosis in Sudan: A systematic review and meta-analysis

K Hajissa, M Marzan, MI Idriss, MA Islam - Antibiotics, 2021 - mdpi.com
Drug-resistant tuberculosis (DR-TB) is still one of the most critical issues impeding
worldwide TB control efforts. The aim of this systematic review and meta-analysis was to …

Tuberculosis in children

S Esposito, C Tagliabue… - Mediterranean journal of …, 2013 - pmc.ncbi.nlm.nih.gov
Tuberculosis (TB) in children is a neglected aspect of the TB epidemic despite it constituting
20% or more of all TB cases in many countries with high TB incidence. Childhood TB is a …

Encapsulation of isoniazid-conjugated phthalocyanine-in-cyclodextrin-in-liposomes using heating method

CI Nkanga, RWM Krause - Scientific Reports, 2019 - nature.com
Liposomes are reputed colloidal vehicles that hold the promise for targeted delivery of anti-
tubercular drugs (ATBDs) to alveolar macrophages that host Mycobacterium tuberculosis …

Global and regional burden of isoniazid-resistant tuberculosis

CM Yuen, HE Jenkins, CA Rodriguez, S Keshavjee… - …, 2015 - publications.aap.org
BACKGROUND: Isoniazid has been the backbone of tuberculosis chemotherapy for 6
decades. Resistance to isoniazid threatens the efficacy of treatment of tuberculosis disease …

Differences between pediatric extra-pulmonary and pulmonary tuberculosis: a warning sign for the future

I Devrim, H Aktürk, N Bayram, H Apa… - … of hematology and …, 2014 - pmc.ncbi.nlm.nih.gov
Background Tuberculosis (TB) remains a major global health problem. The childhood
tuberculosis has some unique features different which makes the diagnosis more …

Drug resistance and its risk factors among extrapulmonary tuberculosis in Ethiopia: A systematic review and meta-analysis

G Diriba, HH Tola, A Alemu, B Yenew, DF Gamtesa… - PLoS …, 2021 - journals.plos.org
Background Drug-resistant tuberculosis and extrapulmonary tuberculosis are the world
major public health issues. Although some primary studies have been reported on the …