Biomedical applications of Schiff base metal complexes

MN Uddin, SS Ahmed, SMR Alam - Journal of Coordination …, 2020 - Taylor & Francis
Metal complexes of Schiff bases synthesized from condensation of an amine with carbonyl
compounds are widely used for industrial purposes such as catalysts, pigments and dyes …

Synthesis, spectroscopic, DFT calculations, biological activity, SAR, and molecular docking studies of novel bioactive pyridine derivatives

KE Anwer, ZK Hamza, RM Ramadan - Scientific Reports, 2023 - nature.com
Enaminonitrile pyridine derivative was used as a precursor for preparation of fourteen
heterocyclic compounds using both conventional thermal and microwave techniques …

Structural investigations of new tridentate-phenylacetohydrazide Schiff base metal chelates: X-ray diffraction, Hirshfeld surface analyses, DFT, antibacterial and …

FM Elantabli, RG Mohamed, SM El-Medani… - Journal of Molecular …, 2024 - Elsevier
The coordination complexes of a tridentate-phenylacetohydrazide Schiff base (2-
hydroxybenzylidene-2-phenylacetohydrazide, HL) with metal ions, namely, iron (II), zinc (II) …

Metal incorporated aminothiazole-derived compounds: synthesis, density function theory analysis, in vitro antibacterial and antioxidant evaluation

SH Sumrra, Z Arshad, W Zafar… - Royal Society …, 2021 - royalsocietypublishing.org
The present study advocates the combined experimental and computational study of metal-
based aminothiazole-derived Schiff base ligands. The structure and electronic properties of …

Synthesis, spectral characterisation, in vitro cytotoxicity, antimicrobial, antioxidant, DFT and molecular docking studies of Ru (III) complexes derived from amide-based …

Subhash, Jyoti, M Gupta, A Phor… - Research on Chemical …, 2024 - Springer
It is absolutely essential to combat some classes of tumours since they are thought to pose
major health risks, necessitating the discovery and development of efficient anticancer …

New bivalent metal chelates based on an NO-donor Schiff base ligand: synthesis, structural characterization, DFT simulation, biological evaluation, and molecular …

HH El-Shalakany, RM Ramadan, MA Sayed - Inorganic Chemistry …, 2024 - Elsevier
It is crucial to establish a correlation between the chemical structure of transition metal
chelates and their anticipated biological activity to create efficient bioinorganic medications …

Structural characterisation of novel mononuclear Schiff base metal complexes, DFT calculations, molecular docking studies, free radical scavenging, DNA binding …

AA Abdel Aziz, RM Ramadan, ME Sidqi… - Applied …, 2023 - Wiley Online Library
New mononuclear metal complexes (M= Mn (II), Fe (III), Co (II), Ni (II), Cu (II) and Zn (II))
derived from a novel tetradentate N2O2 Schiff base ligand (H2L) were efficiently produced …

Spectroscopic, crystal structural, theoretical and biological studies of phenylacetohydrazide Schiff base derivatives and their copper complexes

SM El-Medani, AA Makhlouf, H Moustafa… - Journal of Molecular …, 2020 - Elsevier
Two phenylacetohydrazide Schiff base derivatives: N'-(1-(2-hydroxyphenyl) ethylidene))-2-
phenylacetohydrazide, HL1, and N'-((1-hydroxynaphthalen-2-yl) methylene)-2 …

Synthesis, spectroscopic, DFT calculations, biological activities and molecular docking studies of new isoxazolone, pyrazolone, triazine, triazole and amide derivatives

KE Anwer, GH Sayed, RM Ramadan - Journal of Molecular Structure, 2022 - Elsevier
Abstract Ethyl-2-cyano-2-(2-(3-nitrophenyl) hydrazono) acetate was synthesized and used
as a versatile reagent for the synthesis of different heterocyclic compounds such as …

Exploration of DNA interaction, antimicrobial and antioxidant studies on binary transition metal complexes with isoxazole Schiff bases: Preparation and spectral …

N Ganji, S Daravath, A Rambabu… - Inorganic Chemistry …, 2020 - Elsevier
Abstract Bidentate Schiff bases L 1 H and L 2 H were synthesized. Mono nuclear complexes
[M (L 1) 2] and [M (L 2) 2] where, M= Cu (II)/Ni (II)/Co (II) were prepared and thoroughly …