Cancer is associated with mutated genes, and analysis of tumour-linked genetic alterations
is increasingly used for diagnostic, prognostic and treatment purposes. The genetic profile of …

The minimally—or non-invasive detection of circulating tumor-derived components in
biofluids, such as blood, liquid biopsy is a revolutionary approach with significant potential …

Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …

Precision medicine and personalized medicine are based on the development of
biomarkers, and liquid biopsy has been reported to be able to detect biomarkers that carry …

Plasmacytoid dendritic cells (pDCs) are important mediators of antiviral immunity through
their ability to produce large amounts of type I interferons (IFNs) on viral infection. This …

Following strong activation signals, several types of immune cells reportedly release
chromatin and granular proteins into the extracellular space, forming DNA traps. This …

Simple Summary Minimal residual disease (MRD) represents a status of the disease which
is assumed to still be present in the body until it is clinically observed by radiology. At this …

Cell separation is a powerful tool in biological research. Increasing usage, particularly within
the tissue engineering and regenerative medicine communities, means that researchers …

Toll-like receptor (TLR)-mediated detection of viral nucleic acids and production of type I
interferons (IFNs) by plasmacytoid dendritic cells (pDCs) are key elements of antiviral …

Dendritic cells (DCs) are professional antigen presenting cells displaying the unique
capability to activate naïve T cells. DCs react to pathogen encounter also by the production …